Saadieh MOHAJER, Robabeh BAHARFAR

9386

Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino reactions

A series of novel 2,5-dioxopyrrolidines were synthesized by the one-pot reaction of coumarin-3-carboxylic acids 1 with thiourea derivatives and alkyl isocyanides in the presence of Fe$_{3}$O$_{4}$ NPs @ lipase as heterogeneous reusable nanobiocatalysts with high yields.

Keywords:

Diastereoselective synthesis, 2 5-dioxopyrrolidine derivatives, biocatalytic reactions,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: 6
Yayıncı: TÜBİTAK

Arşiv

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