Adem DOĞANER, Bülent GÜNERİ, Metin KILINÇ, Adem DOĞANER

Düzenli Orta Düzey Egzersizin Oksidatif Stres ve Serum Prolidaz Düzeyleri Üzerindeki Etkileri: Karşılaştırmalı Bir Çalışma

Amaç: Egzersizin oksidasyon durumu üzerine etkileri halen tartışmalı bir konudur. Ayrıca egzersiz ile sreum prolidaz enzim düzeyleri arasındaki ilişki henüz bildirilmemiştir. Çalışmamızda fiziksel olarak aktif bireyler ile hareketsiz yaşam süren bireylerin oksidatif stres belirteçlerinin ve prolidaz enziminin düzeylerine göre karşılaştırılması amaçlanmıştır. Gereç ve Yöntem: On dokuz ile yirmi iki yaş aralığında ve sağlıklı olan bireyler çalışmaya dahil edildi. İki çalışma grubu oluşturuldu: Egzersiz yapan grup (n=79) ve egzersiz yapmayan grup (n=48). Katılımcılarda glutatyon peroksidaz (GPX), katalaz, malondialdehit, total antioksidan kapasite (TAK), total oksidan kapasite (TOK) ve prolidazın serum düzeyleri çalışıldı. Bulgular istatistiksel analize tabi tutuldu. Sonuç: Çalışma grupları arasında GPX (p=0.558) ve katalaz (p=0.628) düzeylerine göre istatistiksel anlamlı fark bulunmadı. Malondialdehit düzeyi egzersiz yapan grupta, prolidaz düzeyi egzersiz yapmayan grupta anlamlı düzeyde diğer gruba göre yüksekti (p

The Effects of Regular Moderate Intensity Exercise on Oxidative Stress and Serum Prolidase Levels: A Comparative Study

Background:The effects of exercise on oxidation state is still a controversial topic. Additionally, the relation between exercise and serum levels of prolidase enzyme has not been reported so far. We aim to compare sedentary and physically active individuals regarding the levels of oxidative stress biomarkers and prolidase enzyme. Materials and Methods: Healthy individuals, 19-22 years old, were enrolled in this study, encompassing the exercise group (n=79) and the sedentary group (n=48). The serum levels of glutathione peroxidase (GPX), catalase, malondialdehyde, total antioxidant status (TAS), total oxidant status (TOS), and prolidase were assayed. Statistical analyses were applied to the findings. Results: The groups demonstrate insignificant difference regarding the serum GPX (p=0.558) and catalase (p=0.628) levels. The serum levels of malondialdehyde (p

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