E. Mahir GÜLCAN, Tufan KUTLU, Tülay ERKAN, Fügen ÇOKUĞRAŞ

Portal ven trombozlu çocuklarda antikardiyolipin antikorları Orijinal Araştırma

Amaç: Portal ven trombozlu çocuklarda antikardiyolipin antikorlarının sıklığının ve portal vendeki tromboz üzerine etkisinin olup olmadığının araştırılması nbsp; Gereç ve Yöntem: Bu ileriye dönük çalışmaya portal ven trombozlu 20 ve kontrol grubu olarak sağlıklı 20 çocuk alındı Antikardiyolipin IgM ve IgG ölçümleri ELISA yöntemi kullanılarak yapıldı Bulgular: Portal ven trombozlu hastalarda antikardiyolipin IgG düzeyleri 13 9±4 8 GPL ünitesi kontrol grubunda 4 4±1 9 GPL ünitesi p lt;0 05 ; antikardiyolipin IgM düzeyleri portal ven trombozlu hastalarda 10 4±5 9 MPL ünitesi kontrol grubunda 10 4±0 8 MPL ünitesi nbsp; p gt;0 05 bulundu Portal ven trombozlu hastaların yedisinde 35 kontrol grubununun birinde 5 antikardiyolipin IgG p lt;0 05 ve portal ven trombozlu hastaların ikisinde 10 kontrol gurubunun ikisinde 10 antikardiyolipin IgM p gt;0 05 yüksekti gt;10 GPL ve MPL ünitesi nbsp;Çıkarımlar: Çocuklarda antikardiyolipin IgG portal ven trombozu ile anlamlı ilişkilidir nbsp; Türk Ped Arş 2009; 44: 124 6 Anahtar kelimeler: Antikardiyolipin antikorları çocuk portal ven trombozu nbsp;

Anahtar Kelimeler:

Antikardiyolipin antikorları, çocuk, portal ven trombozu

Anticardiolipin antibodies in children with portal vein thrombosis Original Article

Aim: The aim of this study was to evaluate the frequency of anticardiolipin antibodies in children with portal vein thrombosis and nbsp; whether anticardiolipin antibodies have effect on thrombosis in the portal vein Material and Method: IgG and IgM anticardiolipin levels were measured in 20 patients with portal vein thrombosis and in 20 healthy controls using an ELISA method nbsp; nbsp; Results: IgG anticardiolipin nbsp; levels GPL unit were found as 13 9±4 8 in the portal vein thrombosis patients and 4 4±1 9 in the control group p lt;0 05 and IgM anticardiolipin levels MPL unit were found as 10 4±5 9 in the portal vein thrombosis patients and in 10 4±0 8 in the nbsp; control group p gt;0 05 In seven 35 portal vein thrombosis patients and in one 5 in the control group anticardiolipin IgG p lt;0 05 and in two portal vein thrombosis patients 10 and in two in the control group 10 anticardiolipin IgM p gt;0 05 levels were high gt;10 GPL and MPL unit Conclusions: IgG anticardiolipin antibodies are significantly associated with portal vein thrombosis in children Turk Arch Ped 2009; 44: 124 6 Key words: Anticardiolipin antibodies child portal vein thrombosis

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