SummaryModern vaccines are safe and effective but not perfect There is evidence that the immune response is altered in some clinical circumstances such as conditions with immunodeficiency and immunosuppression seizures chronic disease pregnancy diabetes and AIDS The type safety and effectivity of vaccines are very important in these patients As the patient s response to vaccines may be insufficient in the above mentioned conditions the effectivity of the vaccines the frequency of immunization and the primary immunization schedules may be altered In this article types and effectivity of vaccines and immunization schedules in special circumstances are reviewed Key words: Vaccine Immunization

Modern vaccines are safe and effective but not perfect There is evidence that the immune response is altered in some clinical circumstances such as conditions with immunodeficiency and immunosuppression seizures chronic disease pregnancy diabetes and AIDS The type safety and effectivity of vaccines are very important in these patients As the patient s response to vaccines may be insufficient in the above mentioned conditions the effectivity of the vaccines the frequency of immunization and the primary immunization schedules may be altered In this article types and effectivity of vaccines and immunization schedules in special circumstances are reviewed Key words: Vaccine Immunization