Gülcan TÜRKER, Ayşe Sevim GÖKALP, Fatma KARAKUŞ

Erken aminoasit desteğinin çok düşük doğum ağırlıklı bebeklerin büyüme ve nörolojik gelişimi üzerine etkisi

Amaç: Erken aminoasit desteğinin 32. gebelik haftasının altında doğan bebeklerde, postmenstrüel 36. hafta ve düzeltilmiş yaşa göre 18. aylarında nörolojik gelişim ve büyüme üzerine etkilerini değerlendirmektir. Gereç ve Yöntem: Hayatlarının ilk beş gününde ≥3 gr/kg/gün parenteral aminoasit alan bebekler erken grubu, 3 gr/kg/gün’den daha az alanlar geç grubu oluşturdu. Ağırlık, boy, baş çevresi ölçümleri postmenstruel 36. hafta ve düzeltilmiş yaş 18. ayda yapıldı. Nörolojik değerlendirmede Bayley gelişim testi uygulandı.Bulgular: Erken ve geç gruplar arasında doğum ağırlığı arasında fark varken, diğer temel belirgin özellikler açısından fark saptanmadı. 36. gebelik haftasında ve düzeltilmiş yaşa göre 18. aylarında her iki grup arasında boy, baş çevresi ve ağırlık açısından fark saptanmadı. Erken grupta kızların 36. hafta ve 18. ayda baş çevre ölçümlerinin daha iyi olduğu görüldü. Bayley mental ve psikomotor gelişim indeksi ile nörogelişimsel bozulma yönünden farklılık saptanmadı. Çıkarımlar: Erken grupta doğum ağırlığının düşük olmasına rağmen 36. haftada ve 18. ayda geç grup seviyelerini yakalamış olması ve kızlarda daha iyi baş çevresinin elde edilmesinin, erken aminoasit desteğinin büyüme ve nörogelişim üzerine olumlu etkisinin olduğunu düşündürmektedir.

The effect of early parenteral amino acids, on growth and neurodevelopment of very low birth weight infants

Aim: To assess the effect of early parenteral amino acids, on growth and neurodevelopment of very low birth weight infants at 36 weeks’ postmenstrual age and 18 months’ corrected age. Material and Method: Infants who received ≥3 gr/kg per day of parenteral amino acids within the first 5 days of life were considered early group; infants who receive

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