Eozinofilik özofajit Çağrılı Yazar

Özet Eozinofilik özofajit giderek daha çok dikkati çekmekte olan yeni fark edilmiş bir bozukluktur Hastalar gastroözofageal reflü bulguları gösterirler bilinen ya da daha karmaşık reflü tedavilerine yanıt vermezler Endoskopik ve histopatolojik belirteçlerin yanı sıra belirtileri içeren tanısal klavuzların geliştirilmesi klinisyenlerin farkındalığını ve tanı koyulan eozinofilik özofajit sayısını artırmıştır Eozinofilik özofajitin gastroözofageal reflü hastalığından klinik olarak ayrımındaki zorluklar daha belirginleşmiş ve daha bireysel tedavi seçeneklerine ihtiyaç duyulmaya başlanmıştır Hastaların 90 rsquo;ında neden gıda alerjileridir Hastalığın patojenezinin daha iyi şekilde anlaşılması klinik olarak tanımlanmasını sağlayarak tanısal yeterliliği arttıracak ve sonuçta hastaların daha iyi tedavi edilmesini sağlayacaktır Türk Ped Arş 2010; 45: 232 7 Anahtar sözcükler: Çocukluk çağı gıda alerjileri eozinofilik özofajit

Anahtar Kelimeler:

Çocukluk çağı, gıda alerjileri, eozinofilik özofajit

Eosinophilic esophagitis Invited Author

Summary Eosinophilic esophagitis is a recently recognized disorder receiving increasing attention Patients present with symptoms of gastroesophageal reflux and are not responsive to standard or aggressive reflux medications Development of diagnostic guidelines consisting of symptoms as well as endoscopic and histopathologic criteria has improved the awareness of clinicians and the diagnosis of eosinophilic esophagitis The clinically challenging discrimination of eosinophilic esophagitis from gastroesophageal reflux disease has become more obvious and has avoked the need for more individualized therapy options Food allergies are causative in more than 90 of patients A better understanding of the pathogenesis of this disorder would improve the clinical recognition and diagnostic adequacy and ultimately provide patients with more optimal treatment options Turk Arch Ped 2010; 45: 232 7 Key words: Childhood eosinophilic esophagitis food allergies

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