Çocukluk çağı atopik dermatitli hastalarda ve ailelerinde dermatolojik yaşam kalitesi değerlendirilmesi
Amaç: Atopik dermatit; alevlenmelerle seyreden kronik, kaşıntılı, enflamatuvar bir deri hastalığıdır. Bu çalışma, atopik dermatit tanısı almış hasta ve ailelerinin yaşam kalitelerinin nasıl etkilendiğini belirlemek amacıyla planlandı.Gereç ve Yöntemler: Hanifin Rajka tanı ölçütleriyle atopik dermatit tanısı koyulan 120 hasta çocuk ve ailesi çalışmaya alındı. Hastalar aktif ve remisyon olarak iki gruba ayrıldı. SCORAD indeksi ile hastalık şiddeti hafif, orta ve ağır olarak sınıflandırıldı. Total IgE, periferik eozinofil sayısı, alerji deri testi tetkikleri yapıldı. Hastaların okuma yazma bilenleri “Çocuk Dermatoloji Yaşam Kalite İndeksi” isimli anketi kendileri doldurdu.” Bebeklerin Dermatolojik Yaşam Kalite İndeksi” isimli anket aileleri tarafından dolduruldu. Ayrıca her hasta için, “Aile Dermatolojik Yaşam Kalitesi İndeksi” isimli anket ebeveynlerden birisi tarafından dolduruldu.Bulgular: Çalışmaya katılan 120 hastanın 76 tanesi (%63,33) erkek 44 tanesi (%36,66) kız olup yaş ortalaması 4,36±3,52 yıldı. Yaşam kalitesi anket puanları, remisyon grubunda aktif gruba göre istatistiksel olarak anlamlı düşüktü (p
Assessment of dermatological quality of life in patients with childhood atopic dermatitis and their families
Aim: Atopic dermatitis is a chronic, itchy, inflammatory skin disease thatprogresses with exacerbations. This study was planned to determinehow atopic dermatitis affects the quality of life of patients and theirfamilies.Material and Methods: One hundred twenty patients with atopic dermatitis, as diagnosed using the Hanifin Rajka diagnostic criteria, andtheir families were included in the study. The patients were divided intotwo groups as active and remission. Disease severity was classified asmild, moderate, and severe according to the SCORAD index. Total IgE,peripheral eosinophil counts, and allergy skin tests were performed. Literate patients completed the Childrens’ Dermatology Life Quality Indexby themselves. The Infants’ Dermatology Life Quality Index was completed by their families. Also, the Family Dermatological Quality of LifeIndex was completed by one of the parents for each patient.Results: Among the 120 patients who participated in the study, 76 (63.33%)were male and 44 (36.66%) were female. The mean age was 4.36±3.52years. The quality of life survey scores were statistically significantlylower in the remission group compared with the active group (p
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- Sapan N. Atopik dermatit. In: Hasanoğlu E, Bideci A, Düşünsel R, editors. Türkiye Milli Pediatri Derneği, Temel Pediatri kitabı; 2010.p.1446–9.
- Arnold, HL, Odom RB, James WD. Atopic dermatitis, eczema, noninfectious immunodeficiency disorders. In: James W, Berger T, Elston D. Andrews’ diseases of the skin. 8th edition. Philadelphia: WB Saunders Company; 1990.p.68–74.
- Leung DYM, Tharp M, Boguniewicz M. Atopic dermatitis. In: Freedberg IM, Eisen AZ, Wolff K, editors. Fitzpatrick’s dermatology in general medicine, 5th edition. New York: Mc Graw-Hill 1999.p.1464–80.
- Hanifin JM. Atopic dermatitis. In: Moschella SL, Hurley HJ, editors. Dermatology, Thirded. Philadelphia: WB. Saunders Company;1992.p.441–64.
- Savaskan H. Atopik dermatit. In: Tüzün Y, Kotagyan A, Aydemir EH, Baransu, editors. Dermatoloji. 2nd edition. Nobel Tıp Kitapevleri;1994.p.257–65.
- Oztürkcan S, Ermertcan AT, Eser E, Sahin MT. Cross validation of the Turkish version of dermatology life quality index. Int J Dermatol 2006; 45: 1300–7.
- Weidinger S, Novak N. Atopic dermatitis. Lancet 2016; 387: 1109–22.
- Williams H, Stewart A, von Mutius E, Cookson W, Anderson HR; International Study of Asthma and Allergies in Childhood (ISAAC) Phase One and Three Study Groups. Is eczema really on the increase worldwide?. J Allergy Clin Immunol 2008; 121: 947–54.e15.
- Ben-Gashir MA, Seed PT, Hay RJ. Predictors of atopic dermatitis severity over time. J Am Acad Dermatol 2004; 50: 349–56.
- Rottem M, Darawsha J, Zarfin J. Atopic dermatits in infants and children in Israel: clinical presentation, allergies and outcome. Isr Med Assoc J 2004; 6: 209–12.
- Seyhan M, Kandi Coşkun B, Karıncaoğlu Y, Özcan H, Kalaycı B. Atopic dermatitis: evaluation of sociodemographical and clinical characteristics in childhood and adolescence. Türkiye Klinikleri J Dermatol 2005; 15: 11–4.
- Arıkan Ç, Bahçeciler NN. Atopik dermatit. T Klin Allerji-Astım 2001; 3: 86–93.
- Borres MP, Odelram H, Irander K, Kjellman NI, Björkstén B. Peripheral blood eosinophilia in infants at 3 months of age is associated with subsequent development of atopic disease in early childhood. J Allergy Clin Immunol 1995; 95: 694–8.
- Kägi MK, Joller-Jemelka H, Wüthrich B. Correlation of eosinophils, eosinophil cationic protein and soluble interleukin-2 receptor with the clinical activity of atopic dermatitis. Dermatology 1992; 185: 88–92.
- Yoshizawa Y, Nomaguchi H, Izaki S, Kitamura K. Serum cytokine levels in atopic dermatitis. Clin Exp Dermatol 2002; 27: 225–9.
- Patrizi A, Guerrini V, Ricci G, Neri I, Specchia F, Masi M. The natural history of sensitizations to food and aeroallergens in atopic dermatitis: a 4-year follow-Up. Pediatr Dermatol 2000; 17: 261–5.
- Ricci G, Dondi A, Patrizi A. Useful tools for the management of atopic dermatitis. Am J Clin Dermatol 2009; 10: 287–300.
- Oranje AP, Glazenburg EJ, Wolkerstorfer A, de Waard-van der Spek FB. Practical issues on interpretation of scoring atopic dermatitis: the SCORAD index, objective SCORAD and the three-item severity score. Br J Dermatol 2007; 157: 645–8.
- Erturan İ, Aktepe E, Didar Balcı D, Yıldırım M, Sönmez Y, Ceyhan AM. Evaluation of self-esteem and dermatological quality of life in adolescents with atopic dermatitis. Turkderm 2013; 47: 39–44.
- Basra MK, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. Br J Dermatol 2008; 159: 997–1035.
- Mollaoğlu M. Kronik hastalıklarda yaşam kalitesi ve hemşirelik. 2. Sağlıkta Yaşam Kalitesi Kongre Özet Kitabı 2007.p.9–10.
- Pınar R. Sağlıkla ilgili yaşam kalitesi. Sendrom 1997; 9: 117–24.
- Oh SH, Bae BG, Park CO, et al. Association of stress with symptoms of atopic dermatitis. Acta Derm Venereol 2010; 90: 582–8.
- Dertlioğlu SB, Cicek D, Balci DD, Halisdemir N. Dermatology life quality index scores in children with vitiligo: comparison with atopic dermatitis and healthy control subjects. Int J Dermatol 2013; 52: 96–101.
- Linnet J, Jemec GB. An assessment of anxiety and dermatology life quality in patients with atopic dermatitis. Br J Dermatol 1999; 140: 268–72.
- Öztürkcan S, Aydemir Ö, İnanır I. Akne vulgarisli hastalarda yaşam kalitesi. T Klin Dermatol 2002; 12: 131–4.
- Morgan M, McCreedy R, Simpson J, Hay RJ. Dermatology quality of life scales--a measure of the impact of skin diseases. Br J Dermatol 1997; 136: 202–6.