Çocuk böbrek nakli alıcılarında viral seroprevalans

Amaç: Böbrek nakli sonrası ortaya çıkan viral enfeksiyonlar nakledilenböbreğe zarar verebilmekte ve hatta bazen hastanın kaybedilmesineneden olabilmektedir. Bu çalışmanın amacı; böbrek nakli planlanan ço cuk hastalardaki viral enfeksiyon etkenlerine ait seropozitivite sıklığınınsaptanmasıdır. Gereç ve Yöntemler: Akdeniz Üniversitesi Tıp Fakültesi Hastanesi’nde2008-2018 tarihleri arasında böbrek nakli yapılmış çocuk hastaların ka yıtları geriye dönük tarandı. Böbrek nakli öncesi değerlendirilen Epste in-Barr virus, sitomegalovirus, hepatit A virus, hepatit B virus, suçiçeği,kızamık, kızamıkçık ve kabakulak serolojileri kaydedildi. Seronegatif veseropozitif hastalara ait özellikler karşılaştırıldı; seropozitiviteye etkieden etkenler araştırıldı. Bulgular: Çalışmaya ortalama yaşı 16.7±6.2 yıl ve ortalama böbrek nakliyapılma yaşı 11.4±5.0 yıl olan 253 çocuk hasta dahil edildi. Aşı ile ön lenebilir viral etkenler için böbrek nakli öncesi seropozitivite oranlarısırasıyla hepatit B virus %89.7, hepatit A virus %60.5, kızamık %78.7, kı zamıkçık %88.1, kabakulak %61.2 ve suçiçeği %71.9 bulundu. Sitomega lovirus seropozitifliği %92.1 iken Epstein-Barr virus için bu or

Viral seroprevalence in pediatric kidney transplantrecipients

Aim: Viral infections commonly affect kidney transplant recipients and may lead to graft failure and death. The aim of this study was to evaluate the antibody seroprevalence against viral agents in kidney transplant recipients.Material and Methods: The records of children who underwent kidney transplantation between 2008 and 2018 in Akdeniz University Faculty of Medicine were retrospectively reviewed. Epstein-Barr virus, cytomegalovirus, hepatitis A virus, hepatitis B virus, varicella, measles, rubella and mumps serologies evaluated before transplantation, were recorded. The clinical characteristics of seronegative and seropositive patients were compared, and factors that affected seropositivity were investigated.Results: The study included 253 children with a mean age of 16.7±6.23 years. The mean age at transplantation was 11.4±5.01 years. The seropositivity rates for vaccine-preventable viral infections varied: hepatitis B 89.7%, hepatitis A 60.5%, measles 78.7%, rubella 88.1%, mumps 61.2%, and varicella 71.9%. Cytomegalovirus seropositivity was 92.1% and Epstein-Barr virus seropositivity was 82.2%. Hepatitis B antibody positivity was 91.8% in patients undergoing hemodialysis, 94.5% in

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