Mohammad Eslami JOUYBARİ, Anahita NOSRATİ, Marzieh BATHAEİ, Elham Sadat BANİMOSTAFAVİ, Mohammad Mehdi Ghaffari HAMEDANİ, Abdolrahim AHMADİ

Synchronous Burkitt’s Lymphoma of Breast and Colonin a Female Patient: A Report of a Case and Review ofLiterature

Burkitt’s lymphoma (BL) is a highly aggressive cancer of B-cells, which is more prevalent in African children. Extranodal involvement of the BL is not a common entity. Herein, we report a young woman who referred to University hospital due to rectorrhagia and breast swelling. Colonoscopy examination revealed a large tumoral lesion of 5×6 cm with superficial ulceration in proximal of ascending colon. Computed tomography (CT) scan of the abdomen showed a 55×42 mm mass in ascending colon and caecum. No lymphadenopathy, splenomegaly and hepatomegaly were reported. Breast ultrasound was performed showed a 24×11 mm hypoechoic heterogeneous mass in the left breast. Bone marrow biopsy was normal. Immunohistochemical assay of colon and breast biopsies confirmed the diagnosis of primary BL. After four courses of chemotherapy, PET-CT revealed complete remission and no sign of metastasis. Since BL is a rapidly-growing neoplasm, prompt diagnosis and treatment can prevent unnecessary surgery and consequences of delay in treatment.

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