Oğuz Hilal SOYDİNÇ, Hakan ÇAMLICA, Nejat DALAY, Derya DURANYILDIZ, Vildan YASASEVER, Faruk TAŞ, Kaytan Esra SAĞLAM

Matriks metalloproteinazlar ve akciğer kanseri

AMAÇ Bu çalışmada akciğer kanserli hastalarda matriks metalloproteinaz- 9 (MMP-9) ve doku matriks metalloproteinaz inhibitörü- 1'in (TIMP-1) tedavi öncesi düzeylerinin belirlenmesi amaçlandı.GEREÇ VE YÖNTEM Çalışmamızda cerrahi ve radyoterapi uygulanmamış 20 akciğer kanserli hastada MMP-9 ve TIMP-1 değerleri ELISA yöntemi ile belirlendi ve sağlıklı kontrol grubu ile karşılaştırıldı (n=20).BULGULAR Hastaların MMP-9 (p

Matrix metalloproteinases and lung cancer

OBJECTIVES The aim of this study was to determine the pretreatment levels of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1) in lung cancer patients.METHODS We investigated the serum MMP-9 and TIMP-1 values in 20 lung cancer patients by ELISA and the results were compared with the controls (n=20).RESULTS MMP-9 (p

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