In Vivo Dosimetry In External Radiotherapy

In Vivo Dosimetry In External Radiotherapy

Radiotherapy is a cancer treatment that uses ionizing radiation to kill or prevent the proliferation of cancerous cells, while also aiming to minimize the damage to healthy tissue. To achieve this in the most effective manner, many radiotherapy machines and treatment techniques have been developed. Today, advanced radiotherapy techniques, such as intensity-modulated radiotherapy, image-guided radiotherapy, and intensity-modulated arc therapy, are frequently being used in cancer treatments. These techniques are applied via computer-controlled devices; therefore, they need to be closely monitored to ensure the dose administered to the patient is as planned. It is important to check the accuracy of the plan to ensure that the correct dose is administered to the patient during treatment. The accuracy of the administered dose can be determined by in vivo dosimetry (IVD). Different measurement devices are used for IVD. In this article, the characteristics of IVD and its measurement systems will be reviewed

___

  • 1. Khan FM. The Physics of Radiation Therapy. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2010.
  • 2. Bilge H, Küçücük H, Yöndem S, Çakır A. Surface and build-up region dose characteristics for high energy photons. Turk J Oncol 2006;21(4):168–73.
  • 3. O’Shea E, McCavana P. Review of surface dose detectors in radiotherapy. J Radiother Pract 2003;3(2):69– 76.
  • 4. Srivastava RP, De Puysseleyr A, De Wagter C. Skin dose assessment in unmodulated and intensity-modulated radiation fields with film dosimetry. Radiat Meas 2012;47(7):504–11.
  • 5. Van Dam J, Marinello G. Methods for In Vivo Dosimetry in External Radiotherapy. 2nd ed. Brussels: ESTRO; 2006.
  • 6. International Commission on Radiological Protection. The 2007 Recommendations of the International Commission on Radiological Protection. ICRP Publication 103. Ann ICRP 2007;37:(2-4).
  • 7. International Commission on Radiation Units and Measurement. Determination of Dose Equivalents Resulting from External Radiation Sources (Report 39). Washington: ICRU; 1985.
  • 8. Mijnheer B, Beddar S, Izewska J, Reft C. In vivo dosimetry in external beam radiotherapy. Med Phys 2013;40(7):070903.
  • 9. Scalchi P, Francescon P. Calibration of a mosfet detection system for 6-MV in vivo dosimetry. Int J Radiat Oncol Biol Phys 1998;40(4):987–93.
  • 10.Bulinski K. Kukolowicz P. Characteristics of the metal oxide semiconductor field effect transistors for application in radiotherapy. Pol J Med Phys 2004;10(1):13– 24.
  • 11.Essers M, Mijnheer BJ. In vivo dosimetry during external photon beam radiotherapy. Int J Radiat Oncol Biol Phys 1999;43(2):245–59.
  • 12.Power Semiconductor Devices Version 2 EE IIT. Kharagpur. Available at: www.vidyarthiplus.in. Accessed Dec 1, 2017.
  • 13.Mackie TR, Scrimger JW. Contamination of a 15-MV photon beam by electrons and scattered photons. Ra-diology 1982;144(2):403–9.
  • 14.Piermattei A, Fidanzio A, Stimato G, Azario L, Grimaldi L, D’Onofrio G, et al. In vivo dosimetry by an aSi-based EPID. Med Phys 2006;33(11):4414–22.
  • 15.Kerns JR, Kry SF, Sahoo N, Followill DS, Ibbott GS. Angular dependence of the nanoDot OSL dosimeter. Med Phys 2011;38(7):3955–62.
  • 16.Holmberg O, Coffey M, Knöös T, Cunningham J. Spotlight on in-vivo dosimetry. ROSIS Newsletter 2006. Available at: http://www.rosis.info/docs/spotlight_case2.pdf.
  • 17.Butson M, Chen T, Alzaidi S, Pope D, Butson E, Gorjiara T, et al. Biomed Phys Eng Express 2016;2(4).
  • 18.Araki F, Ikegami T, Ishidoya T, Kubo HD. Measurements of Gamma-Knife helmet output factors using a radiophotoluminescent glass rod dosimeter and a diode detector. Med Phys 2003;30(8):1976–81.
  • 19.Rah JE, Hwang UJ, Jeong H, Lee SY, Lee DH, Shin DH, et al. Clinical application of glass dosimeter for in vivo dose measurements of total body irradiation treatment technique. Radiat Meas 2011;46:40–5.
  • 20.Devic S, Seuntjens J, Abdel-Rahman W, Evans M, Olivares M, Podgorsak EB, et al. Accurate skin dose measurements using radiochromic film in clinical applications. Med Phys 2006;33(4):1116–24.