Tuğba KINAY, Şule ATALAY MERT, Caner KOSE, Sinan KARADENİZ, Yaprak USTUN

Sistemik İnflamasyon Belirteçlerinin Foley Kateter ile Doğum İndüksiyon Başarısını Öngörmedeki Değeri

Amaç: Sistemik inflamasyon belirteçlerinin foley kateter ile doğum indüksiyonu başarısını öngörmedeki değerini araştırmak. Gereç ve Yöntem: Retrospektif kohort çalışmaya foley kateter ile doğum indüksiyonu uygulanan ≥ 37 hafta, tek, canlı, verteks geliş olan düşük riskli gebeler dahil edildi. Doğum indüksiyonu sonrası sezaryen ile doğumun gerçekleşmesi indüksiyon başarısızlığı olarak kabul edildi. Çalışma popülasyonu doğum indüksiyonu sonrası vajinal doğum yapanlar ve sezaryen doğum yapanlar olarak iki gruba ayrıldı. İki grubun demografik ve klinik özellikleri, prepartum tam kan sayımı değerleri, nötrofil/lenfosit oranı ve platelet/lenfosit oranı karşılaştırıldı. Bulgular: Çalışmaya toplam 308 gebe dahil edildi. Olguların 159’unda (%51,6) doğum indüksiyonu sonrası vajinal yolla doğum gerçekleşirken, 149’unda (%48,4) sezaryen doğum ile gebelik sonlandı. Nulliparite oranı sezaryen ile doğum yapan olgularda (%68,5) vajinal yolla doğum yapanlara (%54,1) göre daha yüksek bulundu (p=0,01). Vajinal yolla doğum yapan ve sezaryen doğum gereksinimi olan olguların lökosit sayıları (9804,9 ± 3283,4 h/mm3’e karşı 10437,1 ± 4439,8 h/mm3), nötrofil/lenfosit oranı (4,7 ± 4,1’e karşı 4,4 ± 3,9) ve trombosit/lenfosit (149,3 ± 67,0’e karşı 139,3 ± 50,1) oranı arasında istatistiksel olarak anlamlı bir fark saptanmadı (p>0,05). Sonuç: Doğum indüksiyonu öncesi bakılan sistemik inflamasyon belirteçleri ile doğum indüksiyon başarısı arasında anlamlı ilişki bulunmadı. Bununla birlikte nulliparitenin foley kateter ile doğum indüksiyon başarısızlığı için bir risk faktörü olduğu saptandı.

Anahtar Kelimeler:

Doğum indüksiyonu, nulliparite, sistemik inflamasyon belirteçi, nötrofil/lenfosit oranı, trombosit/lenfosit oranı

The Predictive Value of Systemic Inflammation Markers for the Success of Labor Induction with Foley Catheter

Objective: To investigate the predictive value of systemic inflammatory markers for the success of labor induction with foley catheter. Material and Method: Low-risk pregnancies with a single, live, vertex presentation at ≥37 weeks of gestation who underwent labor induction with a foley catheter were included in this retrospective cohort study. Delivery by cesarean section after labor induction was considered as induction failure. The study population was divided into two groups as those who delivered vaginally after labor induction and those who delivered by cesarean section. Demographic and clinical characteristics, prepartum complete blood count values, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio of the two groups were compared. Results: A total of 308 pregnant women were included in the study. Vaginal delivery was performed in 159 (51.6%) of the cases after labor induction, while pregnancy was terminated by cesarean section in 149 (48.4%) cases. The rate of nulliparity was found to be higher in cases who delivered by cesarean section (68.5%) than those who delivered vaginally (54.1%) (p = 0.01). There was no statistically significant difference between leukocyte counts (9804.9 ± 3283.4 h/mm3 vs. 10437.1 ± 4439.8 h/mm3), neutrophil/lymphocyte ratio (4.7 ± 4.1 vs. 4.4 ± 3.9) and platelet/lymphocyte ratio (149.3 ± 67.0 vs. 139.3 ± 50.1) of cases who delivered vaginally and required cesarean delivery (p>0.05). Conclusion: There was no significant relationship between systemic inflammation markers measured before labor induction and labor induction success. However, nulliparity was found to be a risk factor for the failure of labor induction with foley catheter.

Keywords:

Labor induction, nulliparity, systemic inflammatory markers, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio,

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