İlk Trimesterde Bradikardik Olan Fetuslar Terme Ulaşıyor Mu?

Amaç: İlk trimesterde bradikardi saptanan fetüslerin kontrol grubu ile kıyaslanarak obstetrik ve perinatal sonuçlarının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Retrospektif kohort dizayn edilen bu çalışmayla hastanemizde takip ve tedavisi yapılmış ilk trimesterde bradikardi tespit edilen 58 gebe ve 276 normal gebe kontrol grubu olarak alınarak çalışmaya dahil edildi. Her hasta için fetal kalp hızı, yaş, parite, abortus sayısı, gebelik haftası, vücut kitle indeksi (VKİ), yardımcı üreme teknikleri kullanılıp kullanılmadığı, 11-14 hafta arası ölçülen nukal translusensi (NT) değeri, gebeliğin nasıl sonuçlandığı, doğum haftası, doğum şekli, yenidoğan yoğun bakım ünitesinde kaç gün yatış olduğu, fetal cinsiyet not alındı ve bu iki grubun perinatal sonuçları karşılaştırıldı. Bulgular: Ortalama yaş bradikardik grupta 27.8 ± 6.1 olup, kontrol grubunda 28.2±6.0 idi. İlk trimester NT ortalaması bradikardik grupta 1.56 ± 0.61 olup, kontrol grubunda 1.26 ± 0.34 ölçüldü. Bradikardik grubun NT’si istatistiksel olarak anlamlı düzeyde kontrol grubundan daha fazla idi (p

Do Fetuses Who Are Bradycardic in The First Trimester Reach Term?

Objective: The aim of this study was to evaluate the obstetric and perinatal outcomes of fetuses diagnosed with bradycardia in the first trimester by comparing them with the control group. Material and Method: In this study, which was designed as a retrospective cohort study, 58 pregnant women who were followed up and treated in our hospital and diagnosed with bradycardia in the first trimester were included as the study group. 276 normal pregnant women were included in the study as a control group. For each patient, fetal heart rate, age, parity, number of abortions, gestational week, body mass index (BMI), whether assisted reproductive techniques were used, NT value measured between 11-14 weeks, type of abortion, week of delivery, type of delivery, neonatal intensive care unit admission, number of hospital days, and fetal sex were noted, and the perinatal outcomes of these two groups were compared. Results: The mean age was 27.8 ± 6.1 years in the bradycardic group and 28.2 ± 6.0 years in the control group. The mean value of NT in the first trimester was 1.56 ± 0.61 in the bradycardic group and 1.26 ± 0.34 in the control group, and the NT of the bradycardic group was statistically significantly higher than that of the control group (p

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  • Knudsen UB, Hansen V, Juul S, Secher NJ. Prognosis of a new pregnancy following previous spontaneous abortions. European Journal of Obstetrics & Gynecology and Reproductive Biology. 1991;39(1):31-6.
  • Mackenzie WE, Holmes DS, Newton JR. Spontaneous abortion rate in ultrasonographically viable pregnancies. Obstetrics and gynecology. 1988;71(1):81-3.
  • Doubilet PM, Benson CB. Outcome of first-trimester pregnancies with slow embryonic heart rate at 6–7 weeks gestation and normal heart rate by 8 weeks at US. Radiology. 2005;236(2):643-6.
  • Yapar EG, Ekici E, Gökmen O. First trimester fetal heart rate measurements by transvaginal ultrasound combined with pulsed Doppler: an evaluation of 1331 cases. European Journal of Obstetrics & Gynecology and Reproductive Biology. 1995;60(2):133-7.
  • Hanprasertpong T, Phupong V. First trimester embryonic/fetal heart rate in normal pregnant women. Archives of Gynecology and Obstetrics. 2006;274(5):257-60.
  • Shenker L, Astle C, Reed K, Anderson C. Embryonic heart rates before the seventh week of pregnancy. The Journal of Reproductive Medicine. 1986;31(5):333-5.
  • Ersoy E, Ersoy AÖ, Çelik EY, Özler S, Altay M, Gelişen O. Ultrasonografik Belirteçlerin İlk Trimester Gebelik Sonuçlarını Öngörmedeki Rolü. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2015;12(2):75-9.
  • Laboda L, Estroff J, Benacerraf B. First trimester bradycardia. A sign of impending fetal loss. Journal of ultrasound in medicine. 1989;8(10):561-3.
  • Walker AM, Cannata J, Dowling MH, Ritchie B, Maloney JE. Sympathetic and parasympathetic control of heart rate in unanaesthetized fetal and newborn lambs. Neonatology. 1978;33(3-4):135-43.
  • Qasim SM, Sachdev R, Trias A, Senkowski K, Kemmann E. The predictive value of first-trimester embryonic heart rates in infertility patients. Obstetrics & Gynecology. 1997;89(6):934-6.
  • Brigham SA, Conlon C, Farquharson RG. A longitudinal study of pregnancy outcome following idiopathic recurrent miscarriage. Human Reproduction. 1999;14(11):2868-71.
  • Chittacharoen A, Herabutya Y. Slow fetal heart rate may predict pregnancy outcome in first-trimester threatened abortion. Fertility and sterility. 2004;82(1):227-9.
  • Wilcox AJ, Weinberg CR, O’Connor JF, Baird DD, Schlatterer JP, Canfield RE, et al. Incidence of early loss of pregnancy. New England Journal of Medicine. 1988;319(4):189-94.
  • Wong S, Chau K, Ho L. Fetal bradycardia in the first trimester: an unusual presentation of atrial extrasystoles. Prenatal Diagnosis: Published in Affiliation With the International Society for Prenatal Diagnosis. 2002;22(11):976-8.
  • Liao A, Snijders R, Geerts L, Spencer K, Nicolaides K. Fetal heart rate in chromosomally abnormal fetuses. Ultrasound in Obstetrics and Gynecology: The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2000;16(7):610-3.
  • Sciarrone A, Masturzo B, Botta G, Bastonero S, Campogrande M, Viora E. First-trimester fetal heart block and increased nuchal translucency: an indication for early fetal echocardiography. Prenatal Diagnosis: Published in Affiliation With the International Society for Prenatal Diagnosis. 2005;25(12):1129-32.
Türk Kadın Sağlığı ve Neonatoloji Dergisi-Cover
  • Başlangıç: 2019
  • Yayıncı: Sağlık Bilimleri Üniversitesi Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi