Ratlarda Oral Olarak Verilen Linear Alkil Benzen Sülfonatın Las Serum Ve Karaciğerdeki Üre, Glukoz Ve Total Bilirubin Düzeyleri Üzerine Kronik Etkilerinin Araştırılması
Bu araştırmada ratlara oral olarak verilen Linear Alkil Benzen Sülfonat LAS ’ın serum ve karaciğerdeki glukoz, total bilirubin ve üre düzeyleri üzerine kronik etkileri incelenmiştir. Bu çalışmada LAS’ın %0.002 0.14mg/kg ’lık ve %0.005 0.35mg/kg ’lık dozlarının ratlarda kronik olarak herhangi bir toksisiteye neden olmayacağı ve ratlar için LAS’ın kronik etkilerinin %0.01 0.7mg/kg ile %0.03 2.1mg/kg dozlarında ve 120.günden itibaren gerçekleştiği sonucuna varılmıştır.
Anahtar Kelimeler:
Linear Alkil Benzen Sülfonat, Glukoz, Total Bilirubin, Üre
Chronic Effects Of Linear Alkyl Benzene Sulphonate Las Given By Oral Route On The Levels Of Glucose, Total Bilirubine And Urea In Serum And Liver Of Rats
In this study, ıt was examined the chronic effects of Linear Alkyl Benzene Sulphonate LAS given by oral route, on the levels of glucose, total bilirubine and urea in serum and liver of rats. It was concluded that LAS in doses of 0.002 % 0.14 mg/kg and 0.005 % 0.35 mg/kg may be unimportant in rats because it created non-toxic chronic effects and chronic toxicologic effects of LAS for rats occur in doses of 0.01 % 0.7 mg/kg and 0.03 % 2.1 mg/kg and 120. days after the application.
Keywords:
Linear Alkyl Benzene Sulphonate, Glucose, Total Bilirubine, Urea,
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- ISSN: 0377-9777
- Başlangıç: 1938
- Yayıncı: Türkiye Halk Sağlığı Kurumu
Sayıdaki Diğer Makaleler
S. Aykut AYTAÇ, Birce MERCANOĞLU, Z. Yeşim ÖZBAŞ
CAMPYLOBACTER JEJUNI SPP. JEJUNI’YE BAĞLI BİR BAKTERİYEMİ OLGUSU
Ahmet Celal BAŞUSTAOĞLU, Abdullah KILIÇ, Mustafa ÖZYURT, Vedat TURHAN, Gülşen HASÇELİK
Nizami DURAN, Fügen YARKIN, Adil M. ALLAHVERDİYEV
AFYON BÖLGESİ KAN DONÖRLERİNDE VİRAL ENFEKSİYON ETKENLERİNİN ARAŞTIRILMASI
Mustafa ALTINDİŞ, Funda KOÇOĞLU