Selen ÖZTÜRK, İbrahim ÖZTÜRK, Seher İLHAN

The risk factors associated with postoperative mediastinitis in cardiacsurgery: A systematic review and meta-analysis

Amaç: Bu derlemede, açık kalp cerrahisinden sonramediastinitin risk etkenleri analiz edildi.Çalışmaplanı: Literatür taraması tarih sınırlaması olmadanPubmed, Ovid ve Sciencedirect veritabanlarında uygulandı.Eş zamanlı hastalıkları araştıran çalışmalar dahil edildi.Çalışma bulguları heterojenite durumuna göre rastgele ya dasabit etki modeli ile değerlendirildi.Bul gu lar: Veritabanı taramasından sonra toplam 5009makale elde edildi. Dahil edilme kriterlerini karşılayan131.158 hastanın yer aldığı 35 makale meta analizedahil edildi. Mediastinit için en olası ameliyat öncesirisk etkenleri atriyal fibrilasyon, pulmoner hastalık,diabetes mellitus, renal hastalık, periferik damar hastalığıve sistemik hipertansiyon idi (p0.05). Heterojenite 12 etkenin dördünde(renal, hepatik, nörolojik ve periferik damar hastalıkları)gözlenmedi (I 2

Kalp cerrahisinde ameliyat sonrası mediastinitle ilişkili risketkenleri: Sistematik derleme ve metaanaliz

Background: In this review, we aimed to analyze the riskfactors of mediastinitis after open cardiac surgery.Methods: The literature screening was performed at Pubmed,Ovid, and Sciencedirect databases without date limitation.Studies investigating the co-existing diseases were included.The results of trials were evaluated with random or fixedeffect model according to the heterogeneity.Results: A total of 5009 articles were attained after databasesearching. Thirty five articles were included to the meta-analysis including 131.158 patients who met inclusion criteria.The most possible preoperative risk factors for mediastinitiswere atrial fibrillation, pulmonary disease, diabetesmellitus, renal disease, peripheral vascular disease andsystemic hypertension (p0.05).Heterogeneity was not observed for four (renal, hepatic,neurological and peripheral vascular diseases) of 12 factors(I 2

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