Zülkif TANRIVERDİ, Barış ÜNAL, Dayimi KAYA, Tuğçe ÇÖLLÜOĞLU, Hüseyin DURSUN

Şiddetli aort darlığı olan hastalarda transkateter aort kapak implantasyonunun Tp-e aralığı, Tp-e/QT ile Tp-e/QTc oranları ve Tp-e dispersiyonu üzerine etkisi

Amaç: Bu çalışmada iki farklı biyoprotez kapak ile yapılan transkateter aort kapak implantasyonunun Tp-e, Tp-e/QT ve Tpe/QTc oranları ve Tp-ed gibi yeni ventriküler repolarizasyon belirteçleri üzerindeki etkisi incelendi. Çalışma planı: Medtronic CoreValve (n=40) veya Edwards SAPIEN XT (n=21) kapak ile transkateter aort kapak implantasyonu yapılan toplam 61 hasta (17 erkek, 44 kadın; ort. yaş 78.6±6.5 yıl; dağılım 55-89 yıl) retrospektif olarak incelendi. Elektrokardiyografik parametreler ve sol ventrikül kütle indeksi işlemden önce, işlemden bir gün sonra ve işlemden sonra üçüncü ayda hesaplandı. Bulgular: Tp-e aralığı, Tp-e/QT ile Tp-e/QTc oranları, Tp-ed ve sol ventrikül kütle indeksi başlangıç değerlerine kıyasla, işlemin üçüncü ayında anlamlı ölçüde azaldı (tümü için p

The effect of transcatheter aortic valve implantation on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, and Tp-e dispersion in patients with severe aortic stenosis

Background: In this study, we aimed to investigate the effect of transcatheter aortic valve implantation using two types of bioprosthetic valves on novel ventricular repolarization markers including Tp-e, Tp-e/QT and Tpe/QTc ratios, and Tp-ed.Methods: A total of 61 patients (17 males, 44 females; mean age 78.6±6.5 years; range 55 to 89 years) who underwent transcatheter aortic valve implantation with either a Medtronic CoreValve (n=40) or an Edwards SAPIEN XT valve (n=21) were retrospectively analyzed. The electrocardiographic parameters and left ventricular mass index were calculated prior to the procedure, on postoperative Day 1, and at three months after the procedure.Results: The Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, Tp-ed, and left ventricular mass index significantly reduced at three months of the procedure, compared to baseline values (p

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