Levent CANSEVER, Celalettin KOCATÜRK, Mustafa KAHRAMAN, Gülfidan ARAS, Dilek KANMAZ, Selma ALTUN, Esin TUNCAY, Mehmet Ali BEDİRHAN

Are predicted postoperative function values similar to actual postoperative values in patients with chronic obstructive pulmonary disease and which of the values are most useful in predicting complications?

Bu çalışmada kronik obstrüktif akciğer hastalığında öngörülen ameliyat sonrası akciğer fonksiyonu değerlerinin ameliyat sonrası gerçek değerlere benzer olup olmadığı ve hangi değerin komplikasyonları öngörmede en faydalı olduğu araştırıldı. Ayrıca, akciğer rezeksiyonu geçiren, kronik obstrüktif akciğer hastalığı olan ve olmayan hastaların sonuçlarında ameliyat sonrası akciğer fonksiyonu değerleri açısından farklılık olup olmadığı gösterildi.Çalışmaplanı:Ocak 2010 - Haziran 2011 tarihleri arasında akciğer rezeksiyonu geçirmiş 151 akciğer kanseri hastası içerisinden kronik obstrüktif akciğer hastalığı olan 23 erkek hasta (ort. yaş 62.0±6.9 yıl) çalışma grubuna dahil edilir iken kronik obstrüktif akciğer hastalığı olmayan 24 hasta (22 erkek, 2 kadın; ort. yaş 55.9±9.7 yıl) rastgele kontrol grubu olarak seçildi. Kronik obstrüktif akciğer hastalığı olan hastalardan 14'ü lobektomi, dokuzu pnömonektomi geçirdi. Kronik obstrüktif akciğer hastalığı olmayan 18 hastaya lobektomi uygulanır iken diğer altı hasta pnomonektomi geçirdi. Öngörülen ameliyat sonrası akciğer fonksiyonları ameliyat sonrası bir, beş ve 10. günlerde ve bir, üç ve altıncı aylarda ölçüldü ve değerlendirildi. Cerrahi sürecin özellikleri, komplikasyonlar, mortalite ve ilgili veriler kaydedildi.Bul gu lar: Ameliyat sonrası beşinci günde gerçek akciğer kapasitesi değerleri eşik değerden ve öngörülen ameliyat sonrası değerlerden düşük idi. Kronik obstrüktif akciğer hastalığı olan ve olmayan hastalar arasında ameliyat sonrası akciğer fonksiyonu açısından anlamlı farklılık yok idi. Pnömoni varlığı kronik obstrüktif akciğer hastalığı ve düşük karbon monoksit difüzyon kapasitesi ile ilişkili idi (p=0.007).So nuç: Çalışmamız ameliyat sonrası

Kronik obstrüktif akciğer hastalığında öngörülen ameliyat sonrası fonksiyon değerleri ameliyat sonrası gerçek değerlere benzer midir ve hangi değer komplikasyonları öngörmede en faydalıdır?

This study aims to investigate if predicted postoperative lung function values are similar to actual postoperative values in patients with chronic obstructive pulmonary disease and which of the values are most useful in predicting complications. Also, we aimed to show whether there is a difference in outcomes of patients with or without chronic obstructive pulmonary disease who undergo lung resection surgery on the basis of postoperative lung function values.Methods: Out of 151 lung cancer patients who underwent lung resection between January 2010 and June 2011, 23 male patients (mean age 62.0±6.9 years) with chronic obstructive pulmonary disease were included in the study group, while 24 patients (22 males, 2 females; mean age 55.9±9.7 years) without chronic obstructive pulmonary disease were randomly selected as the control group. Fourteen of the patients with chronic obstructive pulmonary disease underwent a lobectomy and nine underwent a pneumonectomy. Lobectomies were performed on 18 patients without chronic obstructive pulmonary disease, while the other six patients underwent pneumonectomies. The predicted postoperative lung functions of the patients were measured and evaluated postoperatively on the first, fifth, and 10th days and in the first, third, and sixth months. Features of the surgical process, complications, mortality, and related data were recorded.Results: On the fifth postoperative day, actual lung capacity values were lower than the baseline and predicted postoperative values. There were no significant differences in terms of postoperative lung function in patients with or without chronic obstructive pulmonary disease. The occurrence of pneumonia was associated with chronic obstructive pulmonary disease and low diffusing capacity for carbon monoxide(p=0.007). Conclusion: Our study showed that level of

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