The Long-Term Results of the Combination of Dermofat Graft and Platelet Rich Plasma in a Patient with Hemifacial Atrophy: A Case Report

Hemifasiyal atrofi de kontur bozukluklarının düzeltilmesi için birçok cerrahi yöntem kullanılmaktadır. Dermofat greftin yaşayabilirliğini arttırdığı bilinen trombositten zengin plazma ile yağ greftini kombine ettiğimiz bir hastmızdaki uzun dönem sonuçlarını paylaşmak istiyoruz. Hastamız 30 yaşında erkek hasta yüzünün sol yarısında erime şikâyeti ile geldi. Son 5 yıldır yüzdeki erime şikâyetinin ilerlemediğini öğrendik. Diğer tedavi seçeneklerini hasta ile paylaşarak yağ grefti ile eş zamanlı trombositten zengin plazma uygulamaya karar verdik. Estetik açıdan tatmin edici sonuçlar aldık. Trombositten zengin plazma içerdiği büyüme faktörleri ve sitokinler sayesinde yağ greftlerinde ortaya çıkan absorbsiyon ve yağ kistleri oluşumu gibi olumsuz etkileri azaltarak, neovaskülarizasyonu arttırarak yaşayabilen yağ doku miktarını arttırmaktadır. Uzun süren, riskli, donor alanda morbiditeye neden olan serbest flep uygulamalarına kıyasla daha kolay ve tekrarlanabilen bir prosedür olduğundan trombositten zengin plazma ile kombine yağ greftlerinin alternatif olabileceği kanaatindeyiz

Hemifasiyal Atrofide Trombositten Zengin Plazma ve Dermofat Greft Kombinasyonunun Uzun Dönem Sonucu: Olgu Sunumu

There are many surgical techniques for repairing the contour deformities of hemi-facial atrophy. In this report, we aim to present the long-term results of a patient whom we treated with a combination of fat graft and platelet rich plasma, which is known to enhance the viability of the dermofat graft. A 30-year-old male patient was admitted with the complaint of his left hemi-facial atrophy. The anamnesis revealed that the hemifacial atrophy had not been progressing for the last 5 years. We discussed the various treatment choices with the patient and decided to perform a combination of fat graft and the platelet rich plasma, simultaneously. We achieved aesthetically satisfying results. The platelet rich plasma contains growth factors and cytokines and by these contents it decreases the adverse effects in terms of the formation of the absorption and the fat cysts, and it improves the viability of the fat graft by enhancing neovascularization. Compared to free flap procedures, which are time consuming and risky as well as they cause morbidity for donors, the platelet rich plasma combined with fat grafts may be an alternative application for its advantages such as its easy application and reproducible procedure

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