Son dönem böbrek yetersizliğinde uyku bozuklukları

Son dönem böbrek yetersizliğine sahip hastalarda uyku bozuklukları yaygın olarak görülmektedir. Gündüz aşırı uyku hali, huzursuz bacak sendromu, periyodik ekstremite hareket bozukluğu, insomnia, uyku apne sendromu en sık görülen bozukluklardır. Semptomların benzer olması nedeniyle uyku ile ilişkili şikayetler çoğunlukla üremiye bağlı bulgular olarak değerlendirilir, bu da tanıda gecikmelere neden olabilir. Eşlik eden uyku bozuklukları hastaların yaşam kalitesini ve tedaviye uyumunu olumsuz etkilemesinin yanı sıra, mortalite ve morbiditede artışa neden olmaktadır. Bu nedenle kronik böbrek yetersizliğine sahip veya renal replasman tedavisi almakta olan hastalarda, uyku bozuklukları ayrı bir klinik antite olarak değerlendirilmelidir. Bu yazıda, son dönem böbrek yetersizliğinde sık görülen uyku bozukluklarının etyoloji, patogenez ve tedavilerinin literatür bilgileri eşliğinde gözden geçirilmesi amaçlanmıştır.

Sleep disorders in end-stage renal failure

Sleep disorders are common in patients with end-stage renal disease. Daytime sleepiness, restless legs syndrome, periodic limb movement disorder, insomnia, sleep apnea syndrome are the most disturbances. Usually, sleep-related complaints are attributed to uremia because of similar symptoms, and this may cause to delayed diagnosis. Sleep disorders are negative effect on quality of life and compliance to treatment of patients as well as cause increased mortality and morbidity. Therefore, sleep disorders should be evaluated as a different clinical entity in patients with chronic kidney failure or receiving renal replacement therapy. In this article, we aimed to review of etiology, pathogenesis and treatment of common sleep disorders in end-stage renal failure in sight of releated literature information.

___

  • 1. Hanly P. Sleep disorders and end-stage renal disease. Curr Opin Pulm Med 2008; 14: 543-50.
  • 2. ICSD-2 American Academy of Sleep Medicine. Insomnia. In: Sateia MJ, (ed). The international classification of sleep disorders: diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine 2005: 1-31.
  • 3. Holley JL, Nespor S, Rault R. Characterizing sleep disorders in chronic hemodialysis patients. ASAIO Trans 1991; 37: 456-7.
  • 4. Walker S, Fine A, Kryger MH. Sleep complaints are common in a dialysis unit. Am J Kidney Dis 1995; 26: 751-6.
  • 5. Pai MF, Hsu SP, Yang SY, et al. Sleep disturbance in chronic hemodialysis patients: the impact of depression and anemia. Ren Fail 2007; 29: 673-7.
  • 6. Chen HY, Chiang CK, Wang HH, et al. Cognitive–behavioral therapy for sleep disturbance in patients undergoing peritoneal dialysis: a pilot randomized controlled trial. Am J Kidney Dis 2008; 52: 314-23.
  • 7. Hanly P. Sleep apnea and daytime sleepiness in end-stage renal disease. Semin Dial 2004;17:109-14.
  • 8. Parker KP, Bliwise DL, Bailey JL, et al. Daytime sleepiness in stable hemodialysis patients. Am J Kidney Dis 2003; 41: 394-402.
  • 9. Merlino G, Gigli GL, Valente M. Sleep disturbances in dialysis patients. J Nephrol 2008; 21 (Suppl 13): 66-70.
  • 10. ICSD-2 American Academy of Sleep Medicine. Restless legss syndrome. In: Sateia MJ, (ed). The international classification of sleep disorders: diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine, 2005: 178-81.
  • 11. Montplaisir J, Allen RP, Walters AS, et al. Restless legs syndrome and periodic limb movements dyring sleep. In: Kryger MH, Roth T, Dement WC, (eds). Principles and Practise of Sleep Medicine. 4th ed. Philadelphia: W.B. Saunders Company 2005; 839-52.
  • 12. Unruh ML, Levey AS, D’Ambrosio C, et al. Restless legs symptoms among incident dialysis patients: association with lower quality of life and shorter survival. Am J Kidney Dis 2004; 43: 900-9.
  • 13. Earley CJ, Connor JR, Beard JL, et al. Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome. Neurology 2000; 54: 1698-700.
  • 14. ICSD-2 American Academy of Sleep Medicine. Periodic limb movement disorder. In: Sateia MJ, (ed). The international classification of sleep disorders: diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine, 2005; 182-6.
  • 15. Takaki J, Nishi T, Nangaku M, et al. Clinical and psychological aspects of restless legs syndrome in uremic patients on hemodialysis. Am J Kidney Dis 2003; 41: 833-9.
  • 16. Gigli GL, Adorati M, Dolso P, et al. Restless legs syndrome in end-stage renal disease. Sleep Med 2004; 5: 309-15.
  • 17. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of Sleep Medicine Task Force. Sleep 1999; 22: 667-89.
  • 18. Kuhlmann U, Becker HF, Birkhahn M, et al. Sleep-apnea in patients with end-stage renal disease and objective results. Clin Nephrol 2000; 53: 460-6.
  • 19. Young T, Palta M, Dempsey J, et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993; 328: 1230-5.
  • 20. Erten Y, Kokturk O, Yuksel A, et al. Relationship between sleep complaints and proinflammatory cytokines in haemodialysis patients. Nephrology (Carlton) 2005; 10: 330-5.
  • 21. Beecroft J, Pierratos A, Hanly P. Clinical presentation of obstructive sleep apnea in patients with end-stage renal disease. J Clin Sleep Med 2009; 5: 115-21.
  • 22. Weisbord SD, Fried LF, Mor MK, et al. Renal provider recognition of symptoms in patients on maintenance hemodialysis. Clin J Am Soc Nephrol 2007; 2: 960-7.
  • 23. Heslegrave R, Thornley K, Ouwendyk M, et al. Impact of nocturnal hemodialysis on sleep and daytime cognitive functioning in patients with chronic renal failure. Sleep 1998; 21 (Suppl 3): 1.
  • 24. Bloembergen WE, Port FK, Mauger EA, et al. A comparison of cause of death between patients treated with hemodialysis and peritoneal dialysis. J Am Soc Nephrol 1995; 6: 184-91.
  • 25. Lavie P, Hoffstein V. Obstructive sleep apnea syndrome as a risk factor for hypertension: population study. Br Med J 2000; 320: 479-82.
  • 26. Peker Y, Hedner J, Kraiczi H, et al. Respiratory disturbance index; an independent predictor of mortality in CAD. Am J Respir Crit Care Med 2000; 162: 81-6.
  • 27. Spriggs DA, French JM, Murdy JM, et al. Snoring increases the risk of stroke and adversely affects prognosis. Q J Med 1992; 84: 555-62.
  • 28. Benca RM, Quintas J. Sleep and host defenses: a review. Sleep 1997; 20: 1027-37.
  • 29. Beecroft JM, Hoffstein V, Pierratos A, et al. Pharyngeal narrowing in end-stage renal disease: implications for obstructive sleep apnoea. Eur Respir J 2007; 30: 965-71.
  • 30. Anastassov GE, Trieger N. Edema in the upper airway in patients with obstructive sleep apnea syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 86: 644-7.
  • 31. Mendelson WB, Wadhwa NK, Greenberg HE, et al. Effects of hemodialysis on sleep apnea syndrome in end-stage renal disease. Clin Nephrol 1990; 33: 247-51. 32. Pressman MR, Benz RL, Schleifer CR, et al. Sleep disordered breathing in ESRD: acute beneficial effects of treatment with nasal continuous positive airway pressure. Kidney Int 1993; 43: 1134-9.
  • 33. Langevin B, Fouque D, Leger P, et al. Sleep apnea syndrome and end-stage renal disease. Cure after renal transplantation. Chest 1993; 103: 1330-5.
  • 34. Auckley DH, Schmidt-Nowara W, Brown LK. Reversal of sleep apnea hypopnea syndrome in end-stage renal disease after kidney transplantation. Am J Kidney Dis 1999; 34: 739-44.
  • 35. Mendelson WB, Wadhwa NK, Greenberg HE, et al. Effects of hemodialysis on sleep apnea syndrome in end-stage renal disease. Clin Nephrol. 1990; 33: 247-51.
  • 36. Venmans BJ, van Kralingen KW, Chandi DD, et al. Sleep complaints and sleep disordered breathing in hemodialysis patients. Neth J Med 1999; 54: 207-12.
  • 37. Hanly P, Pierratos A. Improvement of sleep apnea in chronic renal failure treated by nocturnal hemodialysis. N Engl J Med 2001; 344: 102-07.
  • 38. Köktürk O, Çiftçi TU. Santral Uyku Apne Sendromu. Tü- berküloz ve Toraks Dergisi 2003; 51: 349-60.
  • 39. Beecroft J, Duffin J, Pierratos A, et al. Enhanced chemoresponsiveness in patients with sleep apnoea and endstage renal disease. Eur Respir J 2006; 28: 151-8.
  • 40. Wilcox I, McNamara SG, Dodd MJ, et al. Ventilatory control in patients with sleep apnoea and left ventricular dysfunction: comparison of obstructive and central sleep apnoea. Eur Respir J 1998; 11: 7-13.
  • 41. Hudgel DW, Chapman KR, Faulks C, et al. Changes in inspiratory muscle electrical activity and upper airway resistance during periodic breathing induced by hypoxia during sleep. Am Rev Respir Dis 1987; 135: 899-906.
  • 42. Onal E, Burrows DL, Hart RH, et al. Induction of periodic breathing during sleep causes upper airway obstruction in humans. J Appl Physiol 1986; 61: 1438-43
Tüberküloz ve Toraks-Cover
  • ISSN: 0494-1373
  • Yayın Aralığı: 4
  • Başlangıç: 1951
  • Yayıncı: Tuba Yıldırım
Sayıdaki Diğer Makaleler

Bilateral ana bronş obstrüksiyonuna yol açan endobronşiyal malign melanom metastazı tedavisinde Diyot lazer

Sedat ALTIN, Mustafa DÜGER, Sinem Nedime SÖKÜCÜ, Nur ÜRER, Ahmet Levent KARASULU, Levent DALAR

The current data on nanoparticles and pleura

Hasan BAYRAM, Öner DİKENSOY

Epidemiological analysis of tuberculosis trends in Ethiopia: 2000-2009

Tilahun NİGATU, Mulu ABRAHA

Sarkoidozda bozulmuş miyokard performansı

Funda COŞKUN, Esra UZASLAN, Dilber YILMAZ, Aysel KADERLİ AYDIN, Sümeyye GÜLLÜLÜ

Kuzey Kıbrıs Türk Cumhuriyeti askeri sağlık personelinde sigara içme sıklığı, nikotin bağımlılığı ve ucuz sigara satışının etkisi

Ziya ŞİMŞEK, Gürkan METİNYURT, Gürkan KUTUCULAROĞLU, Ersin GÜNAY

Acute improvement of pulmonary artery pressure by non-invasive positive pressure ventilation in the patients with hypercapnic respiratory failure

Neşe DURSUNOĞLU, Dursun DURSUNOĞLU, Aylin MORAY, Şükrü GÜR

Bronchoscopic electrocautery therapy of a solitary endobronchial extramedullary plasmacytoma

Akın KAYA, Ayten CANGIR KAYI, Cabir YÜKSEL, Gökhan ÇELİK, Buket AKDOĞAN BAŞA, Mehmet Sebahattin GÜLEŞ, Aydın ÇİLEDAĞ, Işınsu KUZU

Chlorine-induced extensive tracheobronchial necrosis concomitantly benzene-induced pancytopenia presented with severe pneumonia

Nalan ADIGÜZEL, Gökay GÜNGÖR, Zuhal KARAKURT, Reha BARAN, Tülay YARKIN, Ferda AKSOY

Yoğun bakım ünitesine akut solunum yetmezliği ile kabul edilen KOAH olgularında pnömoni varlığının klinik seyre etkisi

Murat YALÇINSOY, Gökay GÜNGÖR, Cüneyt SALTÜRK, Zuhal KARAKURT, Eylem ACARTÜRK, Özlem MOÇİN YAZICIOĞLU, Yelda BAŞBUĞ

Farklı tedavi yöntemlerinin sigara bırakma başarısı üzerine etkileri

Turan ACICAN, Elif ŞEN, Zeynep Pınar ÖNEN, Banu GÜLBAY ERİŞ, Ayperi ÖZTÜRK, Öznur YILDIZ AKKOCA, Gülseren KARABIYIKOĞLU, Sevgi SARYAL