Göğüs hastalıkları yoğun bakım ünitesindeki akut dahili sorunların mortaliteye etkisi

Çalışmamızda göğüs hastalıkları yoğun bakım ünitesi (YBÜ)’nde karşılaşılan akut dahili sorunlar ve akut tedavi uygulamalarında mortaliteyi etkileyen risk faktörleri araştırıldı. İleriye dönük gözlemsel kohort çalışmada, 20 yataklı göğüs hastalıkları YBÜ’de, 2008 yılındaki tüm hastalar çalışmaya alındı. Hastalar; yaşayanlar grup 1, ölenler grup 2 olarak ikiye ayrıldı. Hastaların demografik özellikleri ve akut dahili sorunları (aritmi, akut böbrek-karaciğer yetmezliği, dopamin, doputamin, perlinganit infüzyonu) kayıt edildi. Mortaliteyi etkileyen faktörler için çoklu regresyon analizi uygulandı. Çalışma döneminde 603 hasta vardı; grup 1 n= 503 (%83.4), grup 2 n= 100 (%16.6). Her iki grup yaş ve cinsiyet yönünden benzerdi. Akut dahili sorunlarda mortalite için risk faktörleri odds oranı (OR), %95 güven aralığı (GA), p değeri olarak sırasıyla septik şok OR: 22.52, GA 8.11-62.57, p< 0.000; perlinganit infüzyon gereği OR: 9.28, GA: 1.61-53.37, p< 0.012; aritmi varlığı OR: 7.81, GA: 3.46-17.65, p< 0.000; akut böbrek yetmezliği OR: 2.88, GA: 1.24-6.65, p< 0.013; dopamin ihtiyacı OR: 2.83, GA: 1.06-7.65, p< 0.037 bulundu. Göğüs hastalıkları YBÜ’lerindeki solunum sorunları ön planda olan hastalarda kalp ve böbrek yetmezliği gibi ek dahili sorunlar gelişmesi, solunum yetmezliğine ilave olarak mortalite için ek risk faktörü oluşturmaktadır. YBÜ sayılarında artış bir sağlık politikası olmakla birlikte göğüs hastalıkları kaynaklı YBÜ takibi gereken hastaların dahili diğer sorunlarını da hızla tedavi edebilecek donanıma sahip koşul ve personelin hazır olması gerekmektedir.

The effect of acute internal problems for mortality in respiratory intensive care unit patients

Acute internal problems in the respiratory intensive care unit (ICU) and risk factors affecting mortality in the acute treatment applications were investigated. All patients in 20-bed intensive care unit for chest diseases enrolled to this prospective observational cohort study during 2008. Patients were classified as living in group 1 and deaths in group 2. Demographics and acute internal problems (arrhythmias, acute kidney-liver failure, dopamine, doputamin, perlinganit infusion) were recorded. Multiple regression analysis was performed for factors affecting mortality. There were 603 patients during the study period, group 1, n= 503 (83.4%), group 2, n= 100 (16.6%). Both groups were similar in terms of age and gender. Odds ratio (OR), 95% confidence interval (CI), p value for internal problems of acute risk factors for mortality were found as; septic shock OR: 22.52, CI 8.11-62.57, p< 0.000; need of perlinganit infusion OR: 9.28, CI: 1.61-53.37, p< 0.012; the presence of arrhythmia, OR: 7.81, CI: 3.46-17.65, p< 0.000; acute renal failure, OR: 2.88, CI: 1.24-6.65, p< 0.013 and the need for dopamine OR: 2.83, CI: 1.06-7.65, p< 0.037, respectively. Internal problems such as cardiac and renal dysfunction can devolop in respiratory ICU patients with pulmonary diseases and these problems constitude additional risk factors for mortalitiy. While the number of ICU is increasing with new health policies, each internal requirement and personnel equipped to treat the problem quickly must be considered.

___

  • 1. Nava S, Confalonieri M, Rampullo C, et al. Intermediate respiratory intensive care units in Europe: a European perspective. Thorax 1998; 53: 798-802.
  • 2. Confalonieri M, Gorini M, Ambrosino N, et al. Respiratory intensive care units in Italy: a national cencus and prospective cohort study. Thorax 2001; 56: 373-8.
  • 3. Altıay G, Tabakoğlu E, Özdemir L, et al. Mortality rates and related factors in respiratory intensive care unit patients. Turkish Thoracic Journal 2007; 8: 79-84.
  • 4. Ceylan E, İtil O, Arı G, et al. Factors affecting mortality and morbidity in patients followed in medical intensive care unit. Turkish Thoracic Journal 2001; 2: 6-12.
  • 5. Uçgun İ, Metintaş M, Moral M, et al. To identify mortality rate and high risk patients in non-malignant respiratory intensive care unit patients. Turkish Thoracic Journal 2003; 4: 151-60.
  • 6. Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med 1985; 13: 818- 29.
  • 7. Reinelt P, Karth GD, Geppert A, Heinz G. Incidence and type of cardiac arrhythmias in critically ill patients: a single center experience in a medical-cardiological ICU. Int Care Med 2001; 27: 1466-73.
  • 8. Elsürer R, Afşar B. The course, prognosis and treatment of acute renal failure in intensive care unit. New J Med 2009; 26: 7-10.
  • 9. American College of Chest Physicians Society of Critical Care Medicine Consensus Conference: defi nitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-74.
  • 10. Alberti C, Brun-Buission C, Burchardi H, et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med 2002; 28: 108- 21.
  • 11. Ursavaş A, Ege E, Yüksel EG, et al. The evaluatin of the factors affecting mortality in respiratory intensive care unit. Turkish Journal of Intensive Care Medicine 2006; 6: 43-8.
  • 12. Sun X, Hakim RB, Knaus WA. Prognosis of acute respiratory failure in patients with chronic obstructive pulmonary disease. In: Derenne JP, Whitelaw WA, Similowski T (eds). Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease. New York: Dekker, 1996: 559-77.
  • 13. Günal H, Çalışır HC, Erol A, et al. Mortality in respiratory intensive care unit. Solunum Hastalıkları 2001; 12: 260-7.
  • 14. Viracca M, Clini E, Porta R, et al. Acute exacerbations in patients with COPD: predictors of need for mechanical ventilation. Eur Respir J 1996; 9: 1487-93.
  • 15. Connors AF Jr, Dawson NV, Thomas C, et al. Outcomes after acute exacerbation of severe chronic obstructive lung disease: the SUPPORT investigators. Am J Respir Crit Care Med 1996; 154: 959-67.
  • 16. Ely EW, Baker AM, Evans GW, et al. The prognostic signifi cance of passing a daily screen of weaning parameters. Intensive Care Med 1999; 25: 581-7.
  • 17. Kollef MH, O’Brien JD, Silver P. The impact of gender on outcome from mechanical ventilation. Chest 1997; 111: 434-41.
  • 18. Schönhofer B, Euteneuer S, Nava S, et al. Survival of mechanically ventilated patients admitted to a specialised weaning centre. Intensive Care Med 2002; 28: 908-16.
  • 19. Hill AT, Hopkinson RB, Stableforth DE. Ventilation in a Birmingham intensive care unit 1993-1995: outcome for patients with chronic obstructive pulmonary disease. Respir Med 1998; 92: 156-61.
  • 20. Anon JM, Garcia de Lorenzo A, Zarazaga A, et al. Mechanical ventilation of patients on long-term oxygen therapy with acute exacerbations of chronic obstructive pulmonary disease: prognosis and cost-utility analysis. Intensive Care Med 1999; 25: 452-7.
  • 21. Schönhofer B, Gou JJ, Suchi S, et al. Th e use of APACHE II prognostic system in difficult-to-wean patients after long-term mechanical ventilation. Eur J Anaesthesiol 2004; 21: 558-65.
  • 22. Bion JF. Susceptibility to critical illness: reserve, response and therapy. Intensive Care Med 2000; 26: 57-63.
  • 23. De Mendonca A, Vincent JL, Suter PM, et al. Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 2000; 26: 915-21.
  • 24. Higgins TL, McGee WT, Steingrub JS, et al. Early indicators of prolonged intensive care unit stay: impact of illness severity, physician staffing, and pre-intensive care unit length of stay. Crit Care Med 2003; 31: 45-51.
  • 25. Avasthi G, Sandhu JS, Mohindra K. Acute renal failure in medical and surgical intensive care units-a year prospective study. Ren Fail 2003; 25: 105-13.
  • 26. Waheed U, Williams P, Brett S, et al. White cell count and intensive care unit outcome. Anaesthesia 2003; 58: 180-3.
Tüberküloz ve Toraks-Cover
  • ISSN: 0494-1373
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1951
  • Yayıncı: Tuba Yıldırım
Sayıdaki Diğer Makaleler

Evaluation of diagnostic accuracy of computed tomography to assess the angioarchitecture of pulmonary sequestration

Asiye KANBAY, Nuri TUTAR, Hakan BÜYÜKOĞLAN, Fatma Sema OYMAK, Ertuğrul MAVİLİ, Mehmet BİLGİN, İnci GÜLMEZ, Ramazan DEMİR

A case of pulmonary embolism confirmed by endobronchial ultrasound

Erdoğan ÇETİNKAYA, Sedat ALTIN, Aydın YILMAZ, Atayla GENÇOĞLU, Akif ÖZGÜL, Seda ONUR

Kuş besleyicisi hastalığı (iki olgu nedeniyle)

Murat YALÇINSOY, Esen AKKAYA, Sinem GÜNGÖR, Sevinç BİLGİN, Belma AKBABA

Clinical presentations and diagnostic work-up in sarcoidosis: a series of Turkish cases (clinics and diagnosis of sarcoidosis)

Ömer Tamer DOĞAN, ÖZDEMİR Özlem KUMBASAR, Peri Meram ARBAK, Oğuz UZUN, Gökhan ÇELİK, Erdoğan ÇETİNKAYA, Gül ÖNGEN, Serir ÖZKAN, Enver YALNIZ, ŞAKAR Ayşın COŞKUN, Leyla SAĞLAM, KUNT A. Esra UZASLAN, Levent TABAK, Gülfer OKUMUŞ, Serdar ERTURAN, Benan MÜSELLİM, Fatma Işıl UZEL, Esin YENTÜRK, Metin ÖZK

Bilateral multiple tumor-like endobronchial tuberculosis, diagnosed with bronchoscopic examination

Yasemin SAYGIDEĞER, Sadık ARDIÇ, Özlem SEVER, Burcu OKTAY, Emine SEVGİ, Hikmet FIRAT

Giant mediastinal parathyroid adenoma

Arif Osman TOKAT, Murat ÖZKAN, Sezgin KARASU, Hüseyin ÇAKMAK

Thorax as an extraintestinal target for inflammatory bowel disease

Meral GÜLHAN, Ömür ATAOĞLU, Halil DEĞERTEKİN, Evrim Eylem AKPINAR

Bronkoskopi ünitesi

Demet KARNAK, Elif KÜPELİ

İnvaziv mekanik ventilasyon gerektiren suçiçeği pnömonisi

Bünyamin SERTOĞULLARINDAN, Bülent ÖZBAY

Reliability and validity of the Turkish version of the pediatric sleep questionnaire: a tool for prediction of sleep related breathing disorder

Özge YILMAZ, Ayhan SÖĞÜT, Ekrem KUTLUAY, Hasan YÜKSEL