Arif Osman TOKAT, Murat ÖZKAN, Sezgin KARASU, Hüseyin ÇAKMAK

Giant mediastinal parathyroid adenoma

Paratiroid adenomlar ve paratiroid hiperplazisi primer hiperparatiroidizmin en sık görülen sebepleridir. Paratiroid adenomlar seyrek olarak çok büyük boyutlara ulaşır. Burada mediasten yerleşimli kitle ve hiperkalsemi saptanan 63 yaşındaki kadın hasta sunulmaktadır. Olguda ektopik hipersekretuar paratiroid adenomuna bağlı yüksek intakt parathormon seviyesi saptandı (642 pg/mL). Kesin histolojik tanı paratiroid adenoma olarak rapor edildi. Olgudaki paratiroid adenomu 7 x 5 x 4 cm boyutları ve 145 g ağırlığı ile literatürdeki en büyük kitle idi. Kitle dev boyutlarına rağmen hiperkalsemi semptomlarına yol açmamıştı.

Giant mediastinal parathyroid adenoma

Primary hyperparathyroidism is most commonly caused by either a parathyroid adenoma or parathyroid hyperplasia. Parathyroid adenomas also rarely attain huge proportions. We present a case of a 63-year-old female patient causing hypercalcemia and the mass which is located in the mediastinum. High intact parathormone level secondary to an ectopic hypersecretory parathyroid adenoma were detected (642 pg/mL). It was removed via a right thoracic approach. In this case parathyroid adenoma measuring 7 x 5 x 4 cm and weighing 145 g; to our knowledge the greatest mass reported in the literature. Despite its huge size it did not cause many of the hypercalcemic symptoms.

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