Hans-Jürgen BIERSACK, Mahmut YÜKSEL, Holger PALMEDO, Roland RÖDEL, Michael REINHARDT, Ursula JAEGER

Multimodal imaging with PET-CT in oncology

Pozitron-emisyon tomografi (PET) ile bilgisayarlı tomografinin (BT) birlikte kullanımı (PET-BT) PET'in klinik kullanımını önemli ölçüde artırmıştır. PET-BT, BT'nin yüksek çüzünürlüğünü PET'in yüksek duyarlığıyla birleştirmektedir. PET ve BT sonuçlarının tek incelemede ve aynı cihazla elde edilmesi nedeniyle her iki prosedürün en uygun birleşimi mümkündür. PET ve BT görüntülerinin klasik birleştirilmesine oranla, PET-BT ile PET'in doğruluğu yaklaşık %15 oranında artırılabilir. PET-BT'nin gücünden tam olarak yararlanmak sadece oral veya intravenöz kontrast ajanların kullanılmasıyla mümkündür. BT'nin X- ışını aynı zamanda atenüasyon düzeltmesi için kullanılır. Bu makalede ağırlıklı olarak akciğer kanseri, malign melanom, baş-boyun tümörleri, tiroid tümörleri ve kolorektal kanserler üzerinde durulmuş ve PET-BT'nin görsel gücü olgulara ait görüntüler aracılığıyla ortaya konmuştur.

Anahtar Kelimeler:

Florodeoksiglikoz F18, Görüntü büyütme, Görüntü işleme, bilgisayar destekli, Neoplazm metastazı, Tomografi, x-ışınlı bilgisayarlı, Pozitron-emisyon tomografisi

Onkolojide PET-BT ile multimodal görüntüleme

The combination of PET (positron emission tomography) with CT (computed tomography) has considerably enhanced the clinical application of PET. PET-CT combines the high resolution of CT with the high sensitivity of PET. As PET and CT results are obtained with one machine during one investigation, an optimal fusion of both procedures is possible. The accuracy of PET can be increased by about 15% by PET-CT, compared to conventional fusion of PET and CT images. The potential of PET-CT can only be fully used if contrast agents -either orally or intravenously- are applied. The Xrays of CT may also be used for attenuation correction. This article focuses mainly on PET-CT in lung cancer, malignant melanoma, head and neck tumors, thyroid tumors, and colorectal cancer, with illustrations of some cases documenting the potentials of PET-CT.

Keywords:

Fluorodeoxyglucose F18, Image Enhancement, Image Processing, Computer-Assisted, Neoplasm Metastasis, Tomography, X-Ray Computed, Positron-Emission Tomography,

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