Trombosit sayısı ve ortalama trombosit hacminin tıkayıcı uyku apne sendromu ile ilişkisi
Amaç: Bu çalışmada trombosit sayısı ve ortalama trombosit hacmi OTH ile tıkayıcı uyku apne sendromu TUAS arasındaki ilişki araştırıldı.Hastalar ve Yöntemler: Bu retrospektif çalışmaya Ocak 2013 - Aralık 2014 tarihleri arasında kliniğimizde polisomnografi PSG yapılan 417 TUAS hastası 284 erkek, 133 kadın; ort. yaş 47.9±10.0; dağılım 23-75 yıl dahil edildi. Hastalar apne hipopne indeksine AHİ göre iki gruba ayrıldı. Apne hipopne indeksi
Anahtar Kelimeler:
Ortalama trombosit hacmi, trombosit, polisomnografi, uyku apnesi
The relationship between platelet count and mean platelet volume with obstructive sleep apnea syndrome
Objectives: This study aims to investigate the relationship between platelet count and mean platelet volume MPV with obstructive sleep apnea syndrome OSAS . Patients and Methods: This retrospective study included 417 OSAS patients 284 males, 133 females; mean age 47.9±10.0; range 23 to 75 years who were performed polisomnography PSG in our clinic between January 2013 and December 2014. Patients were divided into two groups according to apnea-hipopnea index AHI . Apnea-hipopnea index <5 was assumed as normal, while AHI ≥5 was assumed as OSAS. Platelet count and MPV values of group with normal AHI and group with OSAS were statistically compared. Apneahipopnea index, REM AHI, non-REM AHI, minimum oxygen saturation, and duration of oxygen saturation remaining below 90% were statistically compared with platelet count and MPV. Results: The mean of platelet count in non-OSAS and OSAS groups were 262.31±65.78 and 252.77±61.86, respectively, with no statistically significant difference between the groups. Mean platelet volume in non-OSAS and OSAS groups were 9.56±1.88 and 9.71±1.57, respectively; however, the difference was not statistically significant. Platelet count increased statistically significantly as AHI, REM AHI, non-REM AHI, and minimum oxygen saturation parameters got impaired. Conclusion: As PSG parameters get impaired, platelet count increases in OSAS patients.
Keywords:
Mean platelet volume, platelet, polysomnography, sleep apnea,
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- ISSN: 2602-4837
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 1991
- Yayıncı: İstanbul Üniversitesi
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