Erdinç AYDIN, Volkan AKDOĞAN, Hasan YERLİ, B. Handan ÖZDEMİR, Beyhan DEMİRHAN

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Parotis bezi non-Hodgkin lenfoması

Tükürük bezi primer malign lenfomalarının çoğu parotis bezinden kaynaklanır. Bu yazıda, parotis bölgesinde ağ- rısız şişlik nedeniyle başvuran ve lenfoma tanısı konan iki hasta sunuldu. Altmış altı yaşındaki erkek hastanın muayenesinde sağ parotis bezi inferiorunda, nispeten hareketli, ağrısız, sert kıvamlı kitle saptandı. Ultrasonog- rafi, bilgisayarlı tomografi BT ve manyetik rezonans gö- rüntüleme MRG incelemelerinden sonra, sağ parotis bezi yüzeyel lobunda, medialde derin loba uzanan solid lezyondan iğne biyopsisi yapıldı ve patolojik inceleme ile büyük B-hücreli lenfoma tanısı kondu. Hastaya CHOP kemoterapi protokolü uygulandı. İkinci hasta daha önce orbital lenfoma nedeniyle ameliyat edilmiş ve CHOP ke- moterapisi görmüştü. Fizik muayenede solda, parotis be- zi kuyruğunda ağrısız kitle ve parotis kuyruğunun inferi- orunda, cilt altında olduğu izlenimi veren 0.5x1 cm çaplı lenf nodu palpe edildi. Bilgisayarlı tomografi ve MRG’de parotis bezi yüzeyel lobunda posteroinferior kesimde, düzensiz konturlu, 2x1 cm boyutlarında solid lezyon gö- rüldü. Lenf nodundan yapılan biyopsi sonucu küçük hüc- reli malign lenfoma tanısı konan hasta evrelendirme, ile- ri inceleme ve tedavisinin planlanması için tıbbi onkoloji bölümüne sevk edildi
Anahtar Kelimeler:

Baş-boyun neoplazileri/patoloji: lenfoma, non-Hodgkin/patoloji, parotis neoplazisi/patoloji

Non-Hodgkin's lymphoma of the parotid gland

Most of the primary malignant lymphomas of the salivary glands originate from the parotid gland. We presented two patients who were admitted with a painless mass in the parotid region and diagnosed to have lymphoma. Physical examination of a 66-year-old male patient showed a rela- tively mobile, painless, and firm mass at the inferior aspect of the right parotid gland. Ultrasonography, computed tomography CT , and magnetic resonance imaging MRI were performed and a needle biopsy was obtained from the solid lesion extending from the right parotid superficial lobe to the medial deep lobe. Pathological examination revealed large B-cell lymphoma. The patient was treated according to the CHOP chemotherapy protocol. The second patient had undergone surgery for orbital lymphoma and received CHOP chemotherapy. On physical examination, there was a painless mass in the parotid cauda on the left and a subcu- taneous lymph node, 0.5x1 cm in size, inferior to the parotid cauda. Computed tomography and MRI showed an irregu- larly contoured solid lesion, 2x1 cm in size, in the posteroin­ ferior aspect of the superficial lobe. Lymph node biopsy yielded a diagnosis of small celi malignant lymphoma. The patient was referred to the medical oncology department for staging, further investigation, and planning of the treatment.
Keywords:

Head and neck neoplasms/pathology lymphoma, nonHodgkin/pathology, parotid neoplasms/pathology,

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  • Hanna E, Wanamaker J, Adelstein D, Tubbs R, Lavertu P. Extranodal lymphomas of the head and neck. A 20- year experience. Arch Otolaryngol Head Neck Surg 1997;123:1318-23.
  • Wulfrank D, Speelman T, Paulwels C, Roels H, De Schryver A. Extranodal non-Hodgkin’s lymphoma of the head and neck. Radiother Oncol 1987;8:199-207.
  • Jacobs C, Hoppe RT. Non-Hodgkin’s lymphomas of head and neck extranodal sites. Int J Radiat Oncol Biol Phys 1985;11:357-64.
  • Fraser RW, Chism SE, Stern R, Fu KK, Buschke F. Clinical course of early extranodal non-Hodgkin's lymphomas. Int J Radiat Oncol Biol Phys 1979;5:177-83.
  • Freeman C, Berg JW, Cutler SJ. Occurrence and progno- sis of extranodal lymphomas. Cancer 1972;29:252-60.
  • Schusterman MA, Granick MS, Erickson ER, Newton ED, Hanna DC, Bragdon RW. Lymphoma presenting as a salivary gland mass. Head Neck Surg 1988;10:411-5.
  • Barnes L, Myers EN, Prokopakis EP. Primary malig- nant lymphoma of the parotid gland. Arch Otolaryngol Head Neck Surg 1998;124:573-7.
  • Rodriguez MA, Hong WK. Lymphoma presenting in the head and neck current issues in diagnosis and manage- ment. In: Paparella MM, Bailey BJ, editors. Advances in otolaryngology head and neck surgery. Vol. 5. St Louis: Mosby-Year Book; 1991. p. 17-36.
  • Finch SC. Leukemia and lymphoma in atomic bomb survivors. In: Boice JD, Fraumeni JF, editors. Radiation carcinogenesis: epidemiology and biological signifi- cance. NewYork: Raven Press; 1984. p. 37-44.
  • Ziegler JL, Beckstead JA, Volberding PA, Abrams DI, Levine AM, Lukes RJ, et al. Non-Hodgkin's lymphoma in 90 homosexual men. Relation to generalized lym- phadenopathy and the acquired immunodeficiency syndrome. N Engl J Med 1984;311:565-70.
  • Choi DS, Na DG, Byun HS, Ko YH, Kim CK, Cho JM, et al. Salivary gland tumors: evaluation with two- phase helical CT. Radiology 2000;214:231-6.
  • Sumi M, Takagi Y, Uetani M, Morikawa M, Hayashi K, Kabasawa H, et al. Diffusion-weighted echoplanar MR imaging of the salivary glands. AJR Am J Roentgenol 2002;178:959-65.
  • Yoshino N, Yamada I, Ohbayashi N, Honda E, Ida M, Kurabayashi T, et al. Salivary glands and lesions: eval- uation of apparent diffusion coefficients with split- echo diffusion-weighted MR imaging--initial results. Radiology 2001;221:837-42. 188
The Turkish Journal of Ear Nose and Throat-Cover
  • ISSN: 2602-4837
  • Yayın Aralığı: 4
  • Başlangıç: 1991
  • Yayıncı: İstanbul Üniversitesi
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