Nazal polipozisli hastalarda yaşam kalitesinin SF-36 ile ölçülmesi, klinik ve laboratuvar verilerle değerlendirilmesi

Amaç: Nazal polipozisli NP hastalarda yaflam kalitesinideğerlendirerek çeflitli klinik, laboratuvar parametrelerinyaflam kalitesi ile iliflkisini arafltırmayı amaçladık. Hastalar ve Yöntemler: Nazal polipozis tanılı 32 hasta öykü, fizik muayene, endoskopi, bilgisayarlı tomografi, nazal smear ve deri testi ile incelendi. Yaflam kalitesi, MOS Short Form-36 SF36 ölçütünün Türkçe versiyonu kullanılarak değerlendirildi.Sonuçların klinik ve laboratuvar veriler ile iliflkisi incelendi.Bulgular: Bilgisayarlı tomografi skoru ile semptom skoruve endoskopik skor arasında zayıf bir iliflki bulunurken p

Quality of life assessment with the use of the SF-36 in patients with nasal polyposis: correlations with clinical and laboratory findings

O bjectives: We evaluated the guality of life of patients with nasal polyposis and sought correlations betvveen clin­ ical and laboratory param eters and guality of life.Patients and Methods: Thirty-two patients 8 females, 24 males; mean age 43 years; range 15 to 68 years with nasal polyposis were evaluated by history, physical exami- nation, endoscopy, computed tom ography CT , nasal smear, and skin prick tests. Guality of life was assessed using the Medical Outcomes Study Short Form 36 SF-36 .Results: The mean CT score showed a weak correlation with symptom and endoscopic scores p<0.05 , vvhereas the latter two scores were not correlated. Ali the SF-36 scales were adversely influenced, particularly including the scores for role limitation caused by emotional problems, general perception of health, vital- ity, and role limitation caused by physical problems. An inverse correlation was found betvveen increasing age and complaints of pain p<0.05 . Symptom scores were correlated only with role lim­ itation caused by emotional problems p<0.05 . Duration of nasal symptoms was correlated with increased scores for role limitation caused by physical problems, mental health, social functioning, and pain p<0.05 . Computed tomography stage was correlated with role limitation caused by emotional problems, pain, and social functioning, vvhereas CT scores shovved correlation only with pain p<0.05 . The presence of asthma adversely influenced general perception of health scores p<0.05 .Conclusion: Nasal polyposis adversely affects the guality of life of patients, the extent of deterioration being more prom inent in certain subscales.

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  • Senior BA, Glaze C, Benninger MS. Use of the Rhinosinusitis Disability Index (RSDI) in rhinologic disease. Am J Rhinol 2001;15:15-20.
  • Radenne F, Lamblin C, Vandezande LM, Ti l l i e - L e b l o n d I, Darras J, Tonnel AB, et al. Quality of life in nasal poly- posis. J Allergy Clin Immunol 1999;104:79-84.
  • Lildholdt T, Rundcrantz H, Bende M, Larsen K. Glucocorticoid treatment for nasal polyps. The use of topical budesonide powder, intramuscular betametha- sone, and surgical treatment. Arch Otolaryngol Head Neck Surg 1997;123:595-600.
  • Gliklich RE, Metson R. A comparison of sinus computed tomography staging systems for outcomes re s e a rch. Am J Rhinol 1994;8:291-7.
  • Lund VJ, Mackay IS. Staging in rh i n o s i n u s i t u s . Rhinology 1993;31:183-4.
  • Ware JE Jr, Sherbourne CD. The MOS 36-item short- form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30:473-83.
  • Aydemir Ö. Konsültasyon-Liyezon Psikiatrisinde yaflam kalitesi ölçümü: Kısa Form-36 (SF-36). Psikiatri, Psikoloji, Psikofarmakoloji Dergisi 1999;7(Ek.2)14-22.
  • Koçyiğit H, Aydemir Ö, Ölmez N. Memifl A. Kısa Form-36 (KF-36)’nın Türkçe versiyonunun güvenilirli- ği ve geçerliliği. İlaç ve Tedavi Dergisi 1999;12:102-6.
  • Ware JE Jr. Snow KK, Kosinski M, Gandek B. SF-36 Health Survey: Manual and interpretation guide. Boston: The Health Institute, New England Medical Center; 1993.
  • Voegels RL, Santoro P, Butugan O, Formigoni LG. Nasal polyposis and allergy: is there a correlation? Am J Rhinol 2001;15:9-14.
  • Settipane GA, Klein DE, Settipane RJ. Nasal polyps. State of the art. Rhinol Suppl 1991;11:33-6.
  • Blomqvist EH, Lundblad L, Anggard A, Haraldsson PO, Stjarne P. A randomized controlled study evaluating medical treatment versus surgical treatment in addition to medical treatment of nasal polyposis. J Allergy Clin Immunol 2001;107:224-8.
  • Johansson L, Akerlund A, Holmberg K, Melen I, Stierna P, Bende M. Evaluation of methods for endoscopic stag- ing of nasal polyposis. Acta Otolaryngol 2000;120:72-6.
  • Stewart MG, Sicard MW, Piccirillo JF, Diaz-Marchan PJ. Severity staging in chronic sinusitis: are CT scan findings related to patient symptoms? Am J Rhinol 1999;13:161-7.
  • Bhattacharyya T, Piccirillo J, Wippold FJ 2nd. Relationship between patient-based descriptions of sinusitis and paranasal sinus computed tomographic findings. Arch Otolaryngol Head Neck Surg 1997;123: 1189-92.
  • Krouse JH. Computed tomography stage, allergy test- ing, and quality of life in patients with sinusitis. Otolaryngol Head Neck Surg 2000;123:389-92.
  • Naclerio RM, deTineo ML, Baroody FM. Ragweed allergic rhinitis and the paranasal sinuses. A comput- ed tomographic study. Arch Otolaryngol Head Neck Surg 1997;123:193-6.
  • Larsen K, Tos M. A long-term follow-up study of nasal polyp patients after simple polypectomies. Eur Arch Otorhinolaryngol 1997;254 Suppl 1:S85-8.
  • Radenne F, Lamblin C, Vandezande LM, Ti l l i e - L e b l o n d I, Darras J, Tonnel AB, et al. Quality of life in nasal poly- posis. J Allergy Clin Immunol 1999;104:79-84.
  • Juniper EF. Assessing quality of life in adults and chil- dren with asthma and rhinitis. ACI International; 1997; 9:55-9.
  • Juniper EF. Measuring health-related quality of life in rhinitis. J Allergy Clin Immunol 1997;99:742-9.
  • Piccirillo J, Edwards DE, Haiduk AM, Thawley SE. Psychometric and clinimetric validity of the 31-item Rhinosinusitis Outcome Measure (RSOM-31). Am J Rhinol 1995;9:297-306.
  • Gliklich RE, Metson R. The health impact of chronic sinusitis in patients seeking otolaryngologic care . Otolaryngol Head Neck Surg 1995;113:104-9.
  • Bousquet J, Bullinger M, Fayol C, Marquis P, Valentin B, Burtin B. Assessment of quality of life in patients with p e rennial allergic rhinitis with the French version of the SF-36 Health Status Questionnaire. J Allergy Clin Immunol 1994;94(2 Pt 1):182-8.