Murat ÖZTÜRK, Kadri İLA, Cihan DÜZGÖL, Gür AKANSEL, Ahmet ALMAÇ

Leptomeningeal karsinomatozise bağlı iki taraflı ani sensörinöral işitme kaybı: Olgu sunumu ve derleme

Leptomeningeal karsinomatozis, solid tümörlerin metastazı sonucu meninksin diffüz infiltrasyonu ile karakterize, nadir görülen bir durumdur. İki taraflı ani işitme kaybı nadir bir başlangıç semptomudur. Bu yazıda iki taraflı ani işitme kaybı ve baş dönmesi olan 44 yaşında bir erkek hasta sunuldu. Manyetik rezonans görüntülemede iki taraflı vestibülokoklear sinir tutulumu görüldü. Beyin omurilik sıvısı sitolojisinde malign hücreler saptandı. Bildiğimiz kadarıyla, daha önce İngilizce literatürde duodenum adenokarsinomuna bağlı leptomeningeal karsinomatozis bildirilmemiştir. İki taraflı ani işitme kaybı olan hastalarda leptomeningeal karsinomatozis göz önünde bulundurulmalıdır

Anahtar Kelimeler:

Sekizinci kraniyal sinir, leptomeningeal karsinomatosis, ani işitme kaybı

Bilateral sudden sensorineural hearing loss caused by leptomeningeal carcinomatosis: case report and review

Leptomeningeal carcinomatosis is a rare condition characterized by diffuse infiltration of the meninges after the metastasis of the solid tumors. Bilateral sudden hearing loss is a rare initial symptom. In this article, we report a 44-year-old male patient with bilateral sudden hearing loss and dizziness. Magnetic resonance imaging showed involvement of the bilateral vestibulocochlear nerves. Malignant cells were detected in cerebrospinal fluid cytology. To the best of our knowledge, leptomeningeal carcinomatosis due to duodenum adenocarcinoma has not been reported before in the English literature. Leptomeningeal carcinomatosis should be kept in mind in patients who have bilateral sudden sensorineural hearing loss.

Keywords:

Eighth cranial nerve, leptomeningeal carcinomatosis, sudden hearing loss,

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