İsmail Önder UYSAL, Togay MÜDERRİS, Kerem POLAT, Salim YÜCE, Sefa GÜLTÜRK

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İdiyopatik ani sensörinöral işitme kaybında işitmenin iyileşmesinde başlangıçtan tedaviye kadar geçen süre prognostic bir belirteç midir?

Amaç: Bu çalışmada idiyopatik ani sensörinöral işitme kaybı İASNİK olan hastalarda semptomların başlangıcından tedaviye başlama zamanına kadar geçen sürenin prognostik bir belirteç olup olmadığı araştırıldı.Hastalar ve Yöntemler: Bu çalışmada Ocak 1992 - Nisan 2010 tarihleri arasında kliniğimizde İASNİK tanısı konmuş 96 hasta 58 erkek, 38 kadın; ort. yaş 37.8±2.5 yıl; dağılım 16-67 yıl retrospektif olarak değerlendirildi. Hastaların tümü 10 gün süreyle hastane yatışı ve yatak istirahati ile dekstran 40 rheomacrodex , pentoksifilin, B vitamin kompleksi ve C vitamin rejimi ile tedavi edildi. Hastalar saf ton odyometrisi ile test edildi. Odyogramlar farklı günlerde ve tedavi sonunda elde edildi.Bulgular: Tedavilerine ilk yedi gün içerisinde başlanan 75 hastanın 45’inde %60 tam iyileşme, 17’sinde %22.66 kısmi iyileşme görüldü, 13’ünde %17.33 ise herhangi bir iyileşme gözlenmedi. Tedavilerine sekizinci günden sonra başlanan 21 hastanın ikisinde %9.52 tam iyileşme görülürken, yedisinde %33.33 kısmi iyileşme görüldü, 12 hastada %57.14 ise herhangi bir iyileşme gözlenmedi.Sonuç: Çalışma sonuçlarımız, işitme kaybının erken döneminde hastaneye başvuran hastalarda tedavi sonucunun daha iyi olduğunu göstermektedir
Anahtar Kelimeler:

İşitme iyileşmesi, idiyopatik ani sensörinöral işitme kaybı, prognostik faktör

Is the time from the onset to the treatment a prognostic indicator for hearing recovery in idiopathic sudden sensorineural hearing loss?

Objectives: This study aims to investigate whether the time from the onset of symptoms to the start of treatment is a prognostic indicator in patients with idiopathic sudden sensorineural hearing loss ISSNHL . Patients and Methods: In this study, 96 patients 58 males, 38 females; mean age 37.8±2.5 years; range 16 to 67 years who were diagnosed with ISSNHL in our clinic between January 1992 and April 2010 were retrospectively analyzed. All patients were treated with dextran 40 rheomacrodex , pentoxifyllin, vitamin B complex and vitamin C regimen over 10 days with hospitalization and bed rest. The patients were tested by pure-tone audiometry. Audiograms were obtained on alternate days and at the end of the treatment. Results: There was a complete recovery in 45 60% of 75 patients whose treatment was started in the first seven days, while a partial recovery was observed in 17 22.66% and no recovery was observed in 13 17.33% . There was a complete recovery in two 9.52% of 21 patients whose treatment was started after the eighth day, while a partial recovery was observed in seven 33.33% and no recovery was observed in 12 57.14% . Conclusion: Our study results suggest that treatment outcomes are better in the patients presenting to hospital at an early stage of loss of hearing.
Keywords:

Hearing recovery, idiopathic sudden sensorineural hearing loss, prognostic factor,

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  • Wilson WR, Byl FM, Laird N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 1980;106:772-6.
  • Fetterman BL, Saunders JE, Luxford WM. Prognosis and treatment of sudden sensorineural hearing loss. Am J Otol 1996;17:529-36.
  • Mattox DE, Simmons FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 1977;86:463-80.
  • Wilson WR, Veltri RW, Laird N, Sprinkle PM. Viral and epidemiologic studies of idiopathic sudden hearing loss. Otolaryngol Head Neck Surg 1983;91:653-8.
  • Hultcrantz E, Stenquist M, Lyttkens L. Sudden deafness: a retrospective evaluation of dextran therapy. ORL J Otorhinolaryngol Relat Spec 1994;56:137-42.
  • Kellerhals B. Acoustic trauma and cochlear microcirculation. An experimental and clinical study on pathogenesis and treatment of inner ear lesions after acute noise exposure. Adv Otorhinolaryngol 1972;18:91-168.
  • Probst R, Tschopp K, Lüdin E, Kellerhals B, Podvinec M, Pfaltz CR. A randomized, double-blind, placebo- controlled study of dextran/pentoxifylline medication in acute acoustic trauma and sudden hearing loss. Acta Otolaryngol 1992;112:435-43.
  • Campbell KC, Klemens JJ. Sudden hearing loss and autoimmune inner ear disease. J Am Acad Audiol 2000;11:361-7.
  • Singleton GT. Goodhill V. “Sudden deafness and round window rupture.” (Laryngoscope 1971;81(9):1462-74). Laryngoscope 1997;107:577-9.
  • Cinamon U, Bendet E, Kronenberg J. Steroids, carbogen or placebo for sudden hearing loss: a prospective double-blind study. Eur Arch Otorhinolaryngol 2001;258:477-80.
  • Gersdorff M, Franceschi D. Value of piracetam in the treatment of sudden idiopathic deafness. Preliminary report. Ann Otolaryngol Chir Cervicofac 1986;103:283- 5. [Abstract]
  • Grandis JR, Hirsch BE, Wagener MM. Treatment of idiopathic sudden sensorineural hearing loss. Am J Otol 1993;14:183-5.
  • Haberkamp TJ, Tanyeri HM. Management of idiopathic sudden sensorineural hearing loss. Am J Otol 1999;20:587-92.
  • Mann W, Beck C, Beck C. Calcium antagonists in the treatment of sudden deafness. Arch Otorhinolaryngol 1986;243:170-3.
  • Redleaf MI, Bauer CA, Gantz BJ, Hoffman HT, McCabe BF. Diatrizoate and dextran treatment of sudden sensorineural hearing loss. Am J Otol 1995;16:295-303.
  • Tucci DL, Farmer JC Jr, Kitch RD, Witsell DL. Treatment of sudden sensorineural hearing loss with systemic steroids and valacyclovir. Otol Neurotol 2002;23:301-8.
  • Byl FM Jr. Sudden hearing loss: eight years' experience and suggested prognostic table. Laryngoscope 1984;94:647-61.
  • Probst R, Tschopp K, Lüdin E, Kellerhals B, Podvinec M, Pfaltz CR. A randomized, double-blind, placebo- controlled study of dextran/pentoxifylline medication in acute acoustic trauma and sudden hearing loss. Acta Otolaryngol 1992;112:435-43.
  • Weinaug P. Spontaneous remission in sudden deafness. HNO 1984;32:346-51. [Abstract]
  • Cvorović L, Deric D, Probst R, Hegemann S. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss. Otol Neurotol 2008;29:464-9.
  • Lacosta JL, Sánchez Galán L, Infante JC. Sudden deafness. Experience at our hospital. Acta Otorrinolaringol Esp 1998;49:189-93. [Abstract]
  • Müderris S, Quante M, Noack H, et al. Sudden sensorineural hearing loss. [in Turkish] Türk ORL Bülteni 1977;2:95-101.
  • Zientalska E, Moszyński B, Kapiszewska D, Czarnocka E, Kownacka E. The results of sudden deafness treatment. Otolaryngol Pol 1998;52:707-12. [Abstract]
  • Sano H, Shitara T, Okamoto M, Hirayama M. Changes in hearing features according to days from onset of sudden deafness. Nihon Jibiinkoka Gakkai Kaiho 1995;98:1909-13. [Abstract]
  • Gavalas G, Goumas P, Dokianakis G. Is there a time limit for the treatment of sudden hearing loss?. Laryngorhinootologie 1992;71:213-6. [Abstract]
  • Shaia FT, Sheehy JL. Sudden sensori-neural hearing impairment: a report of 1,220 cases. Laryngoscope 1976;86:389-98.
  • Mattox DE, Lyles CA. Idiopathic sudden sensorineural hearing loss. Am J Otol 1989;10:242-7.
  • A Tabuchi K, Kusakari J, Ito Z, Takahashi K, Wada T, Hara A. Effect of nitric oxide synthase inhibitor on cochlear dysfunction induced by transient local anoxia. Acta Otolaryngol 1999;119:179-84.
  • Huy PT, Sauvaget E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol 2005;26:896-902.
  • Tran Ba Huy P, Sauvaget E. Idiopathic sudden sensorineural hearing loss is not, at this time, an otologic emergency. Ann Otolaryngol Chir Cervicofac 2007;124:66-71. [Abstract]
  • Wilson WR, Gulya AJ. Sudden sensorineural hearing loss.IN: Cummings CW, Fredrickson JM, Harker LA, et al.,editors: Otolaryngology-head and neck surgery. 2nd Ed. Vol. 4. St Louis CV Mosby, 1993:3219-3224.
  • Nakashima T, Yanagita N. Outcome of sudden deafness with and without vertigo. Laryngoscope 1993;103:1145-9.
  • Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope 1984;94:664-6.
  • Narozny W, Kuczkowski J, Kot J, Stankiewicz C, Sicko Z, Mikaszewski B. Prognostic factors in sudden sensorineural hearing loss: our experience and a review of the literature. Ann Otol Rhinol Laryngol 2006;115:553-8.
  • Suzuki H, Hashida K, Nguyen KH, Hohchi N, Katoh A, Koizumi H, et al. Efficacy of intratympanic steroid administration on idiopathic sudden sensorineural hearing loss in comparison with hyperbaric oxygen therapy. Laryngoscope 2012;122:1154-7.
  • Hughes GB, Freedman MA, Haberkamp TJ, Guay ME. Sudden sensorineural hearing loss. Otolaryngol Clin North Am 1996;29:393-405.
  • Schuknecht HF, Donovan ED. The pathology of idiopathic sudden sensorineural hearing loss. Arch Otorhinolaryngol 1986;243:1-15.
The Turkish Journal of Ear Nose and Throat-Cover
  • ISSN: 2602-4837
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1991
  • Yayıncı: İstanbul Üniversitesi
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