Bernhard SHİCK, Steffi URBSCHAT

6416

Frontal bölge kafa tabanında malign sinir kılıfı tümörü için endonazal yaklaşım

Paranazal sinüsleri ve frontal bölge kafa tabanını et- kileyen malign periferik sinir kılıfı tümörlerine nadir rastlanır. Bu yazıda, frontobazal bölge malign perife- rik sinir kılıfı tümörü saptanan 46 yaflındak erkek hastanın histopatolojik bulguları, sitometrik DNA analizleri ve karflılafltırmalı genomik hibridizasyonun ilk sonuçları sunuldu. Tümör endonazal yaklaflımla çıkarıldı ve üç yıllık izlem sırasında nüksle karflılaflıl- madı. Rinologlar endonazal tümör cerrahisine gide- rek daha sık baflvurmaktadır
Anahtar Kelimeler:

Sinir kılıfı tümörleri, nükleik asit hibridizasyon, paranazal sinus, kafa tabanı

Endonasal approach for frontobasal malignant nerve sheath tumor: a case report

Malignant peripheral nerve sheath tumors MPNST are rarely encountered in the paranasal sinuses and frontal skull base. We present histopathological find- ings, cytometric DNA measurements, and the prelimi- nary results of comparative genomic hybridization studies of a 46-year-old male patient with a frontobasal MPNST. The tumor was resected via the endonasal approach. No tumor recurrence was detected during a follow-up of three years. Rhinologists are being more frequently involved in endonasal tumor resection.
Keywords:

Nerve sheath neoplasms, nucleic acid hybridization, paranasal sinuses, skull base,

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The Turkish Journal of Ear Nose and Throat-Cover
  • ISSN: 2602-4837
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1991
  • Yayıncı: İstanbul Üniversitesi
Arşiv
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