Ahmet EYİBİLEN, İbrahim ALADAĞ, Mehmet GÜVEN, Sema KOÇ, Levent GÜRBÜZLER

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Çocuklarda akut otit media tedavisinde nazal dekonjestan, oral dekonjestan ve oral dekonjestan-antihistaminiklerin etkinliği

Amaç: Bu çalışmada çocuklarda akut otit media tedavisinde ve orta kulak efüzyonunun çözülmesinde nazal dekonjestan, oral dekonjestan ve oral dekonjestan-antihistaminik kombinasyonu içeren ilaçların etkinliği değerlendirildi.Hastalar ve Yöntemler: Akut otit media tanısı konan ve farklı ilaç uygulanarak tedavi edilen 318 çocuğun [160 erkek 179 kulağı and 158 kız 176 kulağı ] toplam 355 kulağı orta kulak sıvısının çözülmesine göre geriye dönük olarak incelendi. Kulakların 151’i yalnızca antibiyotik ve analjezik grup 1 , 64’ü antibiyotik analjezik ve nazal dekonjestanla grup 2 81’i antibiyotik, analjezik ve oral dekonjestanla grup 3 , 59’u ise antibiyotik, analjezik ve oral dekonjestan-antihistaminik kombinasyonu grup 4 içeren ilaçlarla tedavi edilmişlerdi. Orta kulak sıvısı olan çocuklar üç ay takip edildi.Bulgular: Grup 1, 2, 3 ve 4’de inatçı orta kulak sıvısı vardı ve orta kulak sıvısının varlığı birinci ayın sonunda gruplara göre sırasıyla %27.2, %18.8, %25.9 ve %28.8, üçüncü ayın sonunda ise sırasıyla %5.8, %0, %0 ve %5.9 idi. Üçüncü ayın sonunda orta kulak sıvısının çözülmesi açısından yalnızca antibiyotik kullanan ve ilaveten dekonjestanların verildiği gruplar arasında anlamlı bir fark yoktu p>0.05 .Sonuç: Akut otit media tedavisinde hastalığın doğal seyrinde herhangi bir değişikliğe neden olmadıkları için dekonjestan ve antihistaminik içeren ilaçların kullanılmasını önermiyoruz
Anahtar Kelimeler:

Dekonjestan, nazal, orta kulak, sıvısı/enflamasyonu, solunum yolu enfeksiyonu

The effectiveness of nasal decongestants, oral decongestants and oral decongestant-antihistamines in the treatment of acute otitis media in children

Objectives: The aim of this study was to evaluate the effectiveness of nasal decongestants, oral decongestants and oral decongestant-antihistamines in the treatment of acute otitis media and resolution of the middle ear effusion in children. Patients and Methods: 355 ears of 318 children [160 boys 179 ears and 158 girls 176 ears ] who were diagnosed to have acute otitis media and treated for it with different drug regimens were evaluated retrospectively regarding resolution of the middle ear fluid. 151 ears were treated with antibiotics and analgesics group 1 , 64 with antibiotics, nasal decongestants and analgesics group 2 , 81 with antibiotics, oral decongestants and analgesics group 3 , and 59 with antibiotics, oral decongestant-antihistamine combinations and analgesics group 4 . The children with middle ear effusion were followed up for three months. Results: Group 1, 2, 3 and 4 had persistent middle ear effusion and the presence of middle ear effusion was 27.2%, 18.8%, 25.9%, 28.8% at the 1st month and 5.8%, 0%, 0% and 5.9% at the end of the 3rd month, respectively. At the end of the third month, there was no significant difference between the groups regarding the resolution rates of the middle ear fluids in the antibiotic group and decongestants groups p>0.05 . Conclusion: We do not recommend the use of decongestants and antihistamines in the treatment of acute otitis media as they do not change the natural course of the disease.
Keywords:

Decongestants, nasal, middle ear, fluid/inflammation, respiratory tract infection,

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The Turkish Journal of Ear Nose and Throat-Cover
  • ISSN: 2602-4837
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1991
  • Yayıncı: İstanbul Üniversitesi
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