Talih ÖZDAŞ, Utku DOĞAN, Kürşat Murat ÖZCAN, Ayşe Adin SELÇUK, Hüseyin DERE

Alerjinin cerrahi olarak tedavi edilen nazal polipozis prognozuna etkisi

Amaç: Bu çalışmada alerji varlığının cerrahi olarak tedavi edilen nazal polipozis prognozu üzerine etkisi araştırıldı.Hastalar ve Yöntemler: Bu prospektif çalışmaya Ocak 2006 - Aralık 2008 tarihleri arasında kliniğimize başvuran nazal polipozisli 29 hasta 22 erkek, 7 kadın; ort. yaş 45.9, dağılım 21-72 yıl alındı. Hastalar iki gruba ayrıldı. Grup 1’e deri prick testi pozitif olan veya deri prick test kontrendikasyonu olduğu için serum spesifik immünoglobulin E bakılarak alerji pozitifliği tespit edilen 11 hasta alındı. Grup 2’ye ise, alerji testleri negatif olan 18 hasta alındı. Hastaların ameliyat öncesi endoskopik ve radyolojik değerlendirilmeleri yapıldı. Tüm hastalara iki taraflı endoskopik sinüs cerrahisi uygulandı.Bulgular: Grup 1’in ameliyat öncesi ve sonrası endoskopik ve radyolojik değerlendirme sonuçlarının istatistiksel analizi, iyileşmenin anlamlı düzeyde olmadığını gösterdi p>0.05 . Grup 2’nin ameliyat öncesi ve sonrası endoskopik ve radyolojik değerlendirme sonuçlarının istatistiksel analizi ise, anlamlı bir düzelme olduğunu gösterdi sırasıyla, p

Anahtar Kelimeler:

Alerji, endoskopi, nazal polipozis, radyoloji

The effect of allergy on prognosis of surgically treated nasal polyposis

Objectives: This study aims to investigate the effects of allergy existence on prognosis of surgically treated nasal polyposis. Patients and Methods: This prospective study included 29 patients 22 males, 7 females; mean age 45.9 years; range 21 to 72 years admitted to our clinic with nasal polyposis between January 2006 and December 2008. Patients were divided into two groups. Group 1 consisted of 11 patients who had positive results in skin prick test or whose positivity of allergy was confirmed by serum-specific immunoglobulin E, as a skin prick test was contraindicated. Group 2 included 18 patients who had negative allergy test results. Endoscopic and radiological evaluations of the patients were done preoperatively. Bilateral endoscopic sinus surgery was applied to all patients. Results: Statistical analysis of pre- and postoperative endoscopic and radiological evaluation findings in group 1 showed a non-significant improvement p>0.05 . Statistical analysis of pre- and postoperative endoscopic and radiological evaluation findings in group 2 demonstrated a significant improvement p<0.001, p<0.005 respectively . Conclusion: Response to surgical treatment is more limited in nasal polyposis patients with a positive allergy test.

Keywords:

Allergy, endoscopy, nasal polyposis, radiology,

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