Meruyert KOIZHAIGANOVA, İhsan YAŞA, Gürbüz GÜLÜMSER

GÜMÜŞ KATKILI HİDROKSİAPATİT İLE MUAMELE EDİLEN ASTARLIK DERİLERİN ANTİFUNGAL AKTİVİTESİNİN DEĞERLENDİRİLMESİ

Bu çalışmada, mikrodalga yöntemi ile hazırlanan gümüş katkılı hidroksiapatit (Ag-HA) finisaj kompozisyonu içinde deriye uygulanmış ve antifungal etkisi araştırılmıştır. Muamele edilen derilerin yüzey morfolojisi Taramalı Elektron Mikroskobu (SEM) kullanılarak gözlenmiştir. Deri örneklerindeki Ag miktarı İndüktif Eşleşmiş Plazma Optik Emisyon Spektrometresi (ICP-OES) ile tespit edilmiştir. Kontrol deri ve %0 -%5 Ag katkılı hidroksiapatit ile işlenmiş deri örneklerinin Aspergillus niger TEM ve Trichoderma viride TEM mantarlarına karşı antifungal aktiviteleri ASTM D 4576-08:2008 "Wet-blue Derilerin Mantar Gelişimine Karşı Direnci Standart Test Yöntemi"ne göre değerlendirilmiştir. Çalışma sonuçlarına göre, muamele edilen derilerin antifungal performansları hidroksiapatit içindeki Ag konsantrasyonunun artması ile artmıştır. Ayrıca, %2 veya daha fazla Ag içeren gümüş katkılı hidroksiapatit ile muamele edilen deriler daha güçlü bir antifungal aktivite göstermiş ve Ag katkılı hidroksiapatitin deri üzerine bir antifungal madde olarak kullanılabilirliği düşünülmüştür

Anahtar Kelimeler:

Gümüş katkılı hidroksiapatit, Deri, Antifungal aktivite, Mantara karşı direnç

ASSESSMENT OF THE ANTIFUNGAL ACTIVITY OF LINING LEATHER TREATED WITH SILVER DOPED HYDROXYAPATITE

In this study, silver doped hydroxyapatite (Ag-HA) prepared by the microwave method was applied to leather in the finishing composition and its antifungal effect was investigated. The surface morphology of treated leathers was observed using Scanning Electron Microscopy (SEM). The Ag content in leather samples was identified with inductively coupled plasma optical emission spectrometry (ICP-OES). The antifungal activities of the control leather and the 0% – 5% Ag doped hydroxyapatite treated leather samples on the test fungi Aspergillus niger TEM and Trichoderma viride TEM were evaluated according to ASTM D 4576-08:2008 Standard Test Method for Mold Growth Resistance of Wet-Blue Leather. According to the results of the study, the antifungal performances of the treated leather were increased by increasing the concentration of Ag in hydroxyapatite. Moreover, the leather treated with Ag doped hydroxyapatite containing 2% or more of silver showed strong antifungal activity and it was decided that Ag doped hydroxyapatite could be used as an antifungal agent on leathers

Keywords:

Silver doped hydroxyapatite, Leather, Antifungal activity, Mold resistance,

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