Müjdat KARABULUT, Aylin KARALEZLİ, Sinem KARABULUT, Sabahattin SÜL

RETINAL MICROVASCULAR DIFFERENCES IN TYPE 2 DIABETES WITHOUT CLINICALLY APPARENT RETINOPATHY: AN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY

Objective We aimed to determine early microvascular changes in type 2 diabetes mellitus patients without clinically apparent retinopathy by optical coherence tomography angiography. Material and Methods 80 eyes of patients with diabetes mellitus and without clinically apparent retinopathy, and 80 eyes of age and sex-matched healthy participants were included in this observational case-control study. Vessel density in superficial and deep retinal vessel plexus, foveal avascular zone area, and choriocapillaris flow area in a macular 6.00 × 6.00 mm scan size were evaluated and compared. Results The groups were similar for age and gender (p=0.971 and p=1.000, respectively). The mean duration of diabetes was 10.38±6.31 years (range, 1-25 years) in the study group. Choriocapillaris flow area was significantly lower in the study group than in the control group (p

RETİNOPATİ BULGUSU OLMAYAN TİP 2 DİYABETLİ HASTALARDA RETİNAL MİKROVASKÜLER FARKLILIKLAR: OPTİK KOHERANS TOMOGRAFİ ANJİOGRAFİ ÇALIŞMASI

Amaç Bu çalışmada, klinik olarak tespit edilebilen diyabetik retinopati bulgusu olmayan tip 2 diyabetli hastalarda optik koherans tomografi anjiyografi ile mikrovasküler değişimlerin saptanması amaçlanmıştır. Gereç ve Yöntem Çalışma gözlemsel, olgu-kontrol çalışma olarak planlanmıştır. Klinik olarak tespit edilebilen retinopatisi olmayan (Dilate fundus muayenesinde ve fundus fluoresein anjiyografide) 40 tip 2 diyabet hastasının 80 gözü çalışma grubu olarak belirlenmiştir. Yaş ve cinsiyet açısından benzer 40 sağlıklı hastanın 80 sağlam gözü kontrol grubu olarak seçilmiştir. Bütün hastalara tam oftalmolojik muayene sonrası makula merkezli 6x6 mm büyüklüğünde optik koherens tomografi anjiyografi çekimleri yapılmıştır. Derin ve yüzeyel kapiller ağlarda vasküler yoğunluk, foveal avasküler alan, koryokapiller akım alanı parametreleri kontrol grubu ile karşılaştırılmıştır. Bulgular Yaş ve cinsiyet açısından gruplar arasında fark saptanmamıştır (p=0.971 ve p=1.000; sırasıyla). Ortalama diyabet süresi 10.38±6.31 yıl (1-25 yıl aralığında) olarak bulunmuştur. Koryokapiller akım alanı çalışma grubunda anlamlı olarak düşük bulunmuştur (p

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