NANOBAKTERİ: PERİODONTAL VE SİSTEMİK HASTALIKLARIN İLİŞKİSİNDE FARKLI BİR BAKIŞ AÇISI

Nanobakteriler, sıra dışı biçimde küçük boyutlara sahip (50-500 nm), pleomorfik, infeksiyöz, patojenik varlıklar olarak tarif edilmiş ve patogenezlerinde iskelet dışı kalsifikasyonlar bulunan pek çok sistemik hastalıkla ilişkilendirilmiştir. Periodontal hastalığın temel nedeni olan dental plak, bu tip kalsifikasyonlara benzer bir süreçle mineralize olmaktadır ve kalkulus yapısını oluşturmaktadır. Patolojik kalsifikasyonlarında önemli rol oynadıkları varsayılan nanobakterilerin dental kalkulus oluşumuna katkı sağladığı ve periodontal hastalıklar açısından risk oluşturduğu düşünülmektedir. Bu derlemede nanobakterilerin, periodontal hastalıkların patogenezindeki ve sistemik hastalıklar ile ilişkisindeki olası rolü özetlenmiştir.

Anahtar Kelimeler:

Nanobakteri, periodontal hastalık, patogenez

NANOBACTERIA: A DIFFERENT POINT OF VIEW TO THE RELATIONSHIP BETWEEN PERIODONTAL AND SYSTEMIC DISEASES

Nanobacteria have been described as unusually small sized (50-500 nm), pleomorphic, infectious, pathogenic entities and associated with several systemic diseases having extra-skeletal calcifications in their pathogenesis. Dental plaque as the main cause for periodontal disease minerilizes through a process similar to these calcifications and forms calculus. Nanobacteria, considered to be playing a major role in pathologic calcifications, might be participating in dental calculus formation and consisting a risk factor for periodontal diseases. Possible role of nanobacteria in periodontal diseases' pathogenesis and interrelationship with systemic diseases have been summarized in this review.

Keywords:

Nanobacteria, periodontal disease, pathogenesis,

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