Sinem AYDIN, Kadir KINALIOĞLU, Bahar BİLGİN SÖKMEN

Bazı Yapraksı Liken Türlerinin Antifungal Potansiyellerinin ve Antioksidan Kapasitelerinin Değerlendirilmesi

Bu çalışma yapraksı liken türleri olan Flavoparmelia caperata, Xanthoparmelia stenophylla ve Xanthoparmelia conspersa’nın antioksidan ve antifungal potansiyellerinin belirlenmesini amaçlamaktadır. Bu likenlerin bazı antifungal aktivitesi bazı patojenik mantarlara karşı antifungal aktivitesi disk difüzyon metodu ile araştırılmıştır. Likenlerin asetonitril ekstraktları Soksalet ekstraksiyonu ile elde edilmiştir. En yüksek antifungal aktivite (32 mm) F. caperata tarafından C. albicans’a karşı gözlenirken, en düşük antifungal aktivite (10 mm) X. stenophylla likeninden S. cerevisiae’ye karşı elde edilmiştir. CUPRAC deneyinde absorbans değerleri BHT>X. conspersa>F. caperata>X. stenophylla şeklinde sıralanmaktadır. Çalışma sonucunda, bu liken türlerinin yeni antifungal ve antioksidan bileşik geliştirmede potansiyel bir kaynak olabilecekleri sonucuna varılmıştır.

Evaluation of Antifungal Potentials and Antioxidant Capacities of Some Foliose Lichen Species

This work is aimed to assess of antioxidant and antifungal potential ofthe foliose lichen species: Flavoparmelia caperata, Xanthoparmelia stenophyllaand Xanthoparmelia conspersa. The antifungal activity of lichens were studiedagainst some pathogenic fungi by disc diffusion method. The acetonitrile extractsof these lichens were obtained with Soxhlet extraction. While F. caperataexhibited maximum antifungal activity (32 mm) against the C. albicans, theminimum antifungal activity (10 mm) was obtained from X. stenophylla lichenagainst S. cerevisiae. In CUPRAC assay, absorbance values was in order of BHT>X.conspersa>F. caperata>X. stenophylla. As a result of the study, it was concludedthat these lichen species may be a potential source for the development of newantifungal and antioxidant compounds.

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