Mehmet SÖZEN, Zeynep CANTÜRK, Alev SELEK, Berrin ÇETİNASLAN, Burcu SEVİNÇ, Emre GEZER, Damla KÖKSALAN

PAPİLLER TİROİD KARSİNOMUNDA YARARLI BİR BELİRTEÇ OLARAK İNFLAMASYONLA İLİŞKİLİ HEMOGRAM PARAMETRELERİNİN DEĞERLENDİRİLMESİ

Amaç İnflamasyona bağlı hemogram parametreleri son zamanlarda kanser hastalarında faydalı bir belirteç olarak tanımlanmaya başlamıştır. Bu çalışmada, papiller tiroid kanserli (PTC), malignite potansiyeli belirsiz iyi diferansiye tiroid tümörü ve foliküler adenomlu (FA) hastalarda hemogram parametrelerinin karşılaştırılması amaçlandı. Gereç ve Yöntem Çalışmada 287 hastanın verileri analiz edildi. Çalışma popülasyonu 5 farklı gruba ayrıldı. 1. Grup: kontrol, 2. grup: FA, 3. grup: WDT-UMP, 4. grup: metastatik olmayan PTC, 5. grup: metastatik PTC. Ameliyat öncesi yapılan kan testlerini değerlendirdik. Bulgular Ortalama yaş 50 (37-59) idi. Ortalama TSH değeri 1.2 (0.5-2.2) μIU/mL idi. Total tiroidektomi materyalinde saptanan lezyonun ortalama boyutu 1.7 (1.0-3.0) cm idi. Grup 3'te beyaz kan hücreleri (WBC), nötrofiller ve lenfositler grup 4'e göre daha düşüktü (p

Anahtar Kelimeler:

papiller tiroid kanseri, WDT-UMP, foliküler adenom, MPV, RDW

EVALUATION OF INFLAMMATION-RELATED HEMOGRAM PARAMETERS AS A USEFUL MARKER IN PAPILLARY THYROID CARCINOMA

Objective Inflammation-related hemogram parameters have recently started to be defined as a useful marker in cancer patients. In this study, we aimed to comparison of hemogram parameters in papillary thyroid cancer (PTC) patients, well differentiated thyroid tumor of uncertain malignant potential (WDT-UMP) and follicular adenoma (FA). Material and Method The 287 patients’ data were analyzed in study. Study subjects were divided into 5 different groups. 1st group: control, 2nd group: FA, 3rd group: WDT-UMP, 4th group: non-metastatic PTC, 5th group: metastatic PTC. We evaluated the preoperative blood tests. Results The average age was 50 (37-59). The mean TSH value was 1.2 (0.5-2.2) μIU/mL. The mean size of the lesion detected in the total thyroidectomy material was 1.7 (1.0-3.0) cm. White blood cells (WBC), neutrophils and lymphocytes were lower in 3rd group than 4th group (p

Keywords:

papillary thyroid cancer, WDT-UMP, follicular adenoma, MPV, RDW,

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