Measurement of the Penetration Depth in Biological Tissue for Different Optical Powers

In photodynamic therapy, the knowledge of the penetration depth for the light is needed in order to ensure that the adequate optical energy is received by the tumorous tissue. In this study, the optical penetration depth of 635 nm laser light in chicken breast tissue has been measured by using 8 tissue samples with different thicknesses between 2.5 mm and 9.0 mm. Transmitted light intensities through the tissue samples have been measured for 11 different optical power values in the range of 130 mW – 660 mW. Measurement results for each power value have been analyzed according to the Beer-Lambert law. With the help of statistical analyzes, it has been determined that the optical penetration depth in biological tissue does not depend on the optical power.

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