Determination of Resmethrin in Corn Silk Matrix by Gas Chromatography-Flame Ionization Detector (GC-FID)

The use of pesticides provides benefits such as growing food products necessary for life, sustainability of production efficiency and prevention of diseases caused by pests. However, these benefits can turn into negative effects for humans and other living organisms with the use of pesticides in inappropriate doses and application methods. In this study, it was aimed to determine resmethrin, which belongs to the insecticide class, by gas chromatography-flame ionization detector (GC-FID) method. Hence, a suitable temperature program was utilized to determine resmethrin at a certain retention time. Limit of detection (LOD) and limit of quantification (LOQ) values were recorded as 0.02 and 0.08 mg/L under the proposed conditions, respectively. After corn silk sample was extracted using acetonitrile, analytical measurements were carried out to investigate the presence of resmethrin. There was no analytical signal detected that belonged to resmethrin in the analyzed sample. Recovery experiments were performed using external calibration method with spiked samples at three different concentrations and good percent recovery results were obtained between 93 and 97%.

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[1] M. K. Ross, “Pyrethroids,” in Encyclopedia of Environmental Health, Elsevier, 2011, pp. 702–708.
[2] H. Seçilmiş Canbay, S. Öğüt, “Organik ve Organik Olmayan Elmalar ile Bu Elmaları Üreten Kişilerdeki Pestisit Kalıntıları ve Toplam Antioksidan Kapasiteleri,” Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, pp. 1–1, Dec. 2017.
[3] D. S. Chormey, “Determination of Fenobucarb and Chlorbenside in Wastewater and Lake Water Samples by Gas Chromatography Mass Spectrometry” European Journal of Science and Technology, 2021.
[4] G. Rosini, V. Borzatta, C. Paolucci, P. Righi, “Comparative assessment of an alternative route to (5-benzylfuran-3-yl)methanol (Elliott’s alcohol), a key intermediate for the industrial production of resmethrins” Green Chemistry, vol. 10, no. 11, p. 1146, 2008.
[5] M. A. Hassaan, A. El Nemr, “Pesticides pollution: Classifications, human health impact, extraction and treatment techniques,” The Egyptian Journal of Aquatic Research, vol. 46, no. 3, pp. 207–220, 2020.
[6] R. Jayaraj, P. Megha, P. Sreedev, “Review Article. Organochlorine pesticides, their toxic effects on living organisms and their fate in the environment,” Interdisciplinary Toxicology, vol. 9, no. 3–4, pp. 90–100, 2016.
[7] N. Çördük, N. Akıncı, N. Kaya, G. Yücel, C. Akı, “Dodin Fungisitinin Vicia faba L. Bitkisinde Total Protein Miktarı ve Peroksidaz Aktivitesi Üzerine Etkisi,” Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, vol. 20, no. 3, 2016.
[8] R. Le Grand, S. Dulaurent, J. M. Gaulier, F. Saint-Marcoux, C. Moesch, G. Lachâtre, “Simultaneous determination of five synthetic pyrethroid metabolites in urine by liquid chromatography-tandem mass spectrometry: application to 39 persons without known exposure to pyrethroids,” Toxicology Letters, vol. 210, no. 2, pp. 248–53, 2012.
[9] M. Tao, G. Zhang, C. Xiong, J. Pan, “Characterization of the interaction between resmethrin and calf thymus DNA in vitro,” New Journal of Chemistry, vol. 39, no. 5, pp. 3665–3674, 2015.
[10] R. P. Pohanish, “R,” in Sittig’s Handbook of Pesticides and Agricultural Chemicals, Elsevier, pp. 730–737, 2015.
[11] R. A. Simonaitis, R. S. Cail, “Gas-liquid chromatographic determination of resmethrin in corn, cornmeal, flour, and wheat,” Journal - Association of Official Analytical Chemists, vol. 58, no. 5, pp. 1032–1036, 1975.
[12] T. Narahashi, “Mode of action of pyrethroids,” Bulletin of the World Health Organization, vol. 44, no. 1–3, pp. 337–45, 1971.
[13] D. M. Soderlund, J. R. Bloomquist, “Neurotoxic Actions of Pyrethroid Insecticides,” Annual Review of Entomology, vol. 34, no. 1, pp. 77–96, 1989.
[14] US EPA, “Reregistration Eligibility Decision for Ferbam,” Prevention, Pesticides and Toxin Substances, pp. 1–73, 2005.
[15] A. Masiá, C. Blasco, Y. Picó, “Last trends in pesticide residue determination by liquid chromatography–mass spectrometry,” Trends in Environmental Analytical Chemistry, vol. 2, pp. 11–24, 2014.
[16] J.-M. Lin, L.-B. Liu, Y. Liu, “Determination of Pesticide Residues in Fruits and Vegetables by Using GC–MS and LC–MS,” in Handbook of Pesticides, CRC Press, pp. 497–523, 2009.
[17] E. G. Bakırdere, “Simultaneous determination of selected alachlor, bifenox and nitrofen as herbicides in lake, municipal wastewater and soil samples by gas chromatography mass spectrometry,” European Journal of Science and Technology, pp. 108–111, 2018.
[18] H. Budiman, Nuryatini, O. Zuas, “Comparison between GC-TCD and GC-FID for the determination of propane in gas mixture,” Procedia Chemistry, vol. 16, pp. 465–472, 2015.
[19] M. P. Kavvalakis, M. N. Tzatzarakis, A. K. Alegakis, D. Vynias, A. K. Tsakalof, and A. M. Tsatsakis, “Development and application of GC-MS method for monitoring of long-term exposure to the pesticide cypermethrin,” Drug Testing and Analysis, vol. 6, no. S1, pp. 9–16, 2014.
[20] S. Tandon, S. Kumar, N. K. Sand, “Development and Validation of GC-ECD Method for the Determination of Metamitron in Soil,” International Journal of Analytical Chemistry, vol. 2015, pp. 1–5, 2015.
[21] M. Abbasghorbani, A. Attaran, M. Payehghadr, “Solvent-assisted dispersive micro-SPE by using aminopropyl-functionalized magnetite nanoparticle followed by GC-PID for quantification of parabens in aqueous matrices,” Journal of Separation Science, vol. 36, no. 2, pp. 311–319, 2013.
[22] B. Bayrak, “Sudaki Pestisit Kalıntılarının Belirlenmesi için GC-NPD Kullanılarak Method Geliştirilmesi ve Validasyonu,” Journal of the Institute of Science and Technology, vol. 8, no. 1, pp. 133–141, 2018.
[23] E. Forgács, T. Cserháti, “Chromatography | Principles,” in Encyclopedia of Food Sciences and Nutrition, Elsevier, 2003, pp. 1259–1267.
[24] H. Nozawa, K. Minakata, K. Hasegawa, I. Yamagishi, M. Suzuki, T. Kitamoto, K. Watanabe, O. Suzuki, “A fatal case involved in pyrethroid insecticide ingestion: quantification of tetramethrin and resmethrin in body fluids of a deceased by LC–MS/MS,” Forensic Toxicology, vol. 40, no. 1, pp. 189–198, 2022.