Bahar SEVİMLİ DİKİCİER, Bekir Enes DEMİRYÜREK

Vitiligo Hastalarında İnce Lif Nöropatisinin Değerlendirilmesi

Amaç: Bu çalışma, normal standart sinir iletim çalışmaları olan vitiligo hastalarında ince lif nöropatisini tespit etmek için tasarlanmıştır. Meteryal Metod: Bu vaka- kontrol çalışması Mart 2016-Haziran 2016 tarihleri arasında Sakarya Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi Nöroloji Anabilim Dalı'nda ENMG laboratuvarında gerçekleştirildi. Çalışmaya 123 vitiligo hastasından dışlama kriterlerine göre seçilmiş 18-60 yaş arasında 40 vitiligo hastası ile kontrol amaçlı yaşları ve cinsiyetleri eşleştirilmiş 40 sağlıklı birey dahil edildi. Katılımcılar iki gruba ayrıldı (vitiligo ve kontrol grupları). Katılımcıların demografik verileri kaydedildi. İnce lif iletimini değerlendirmek için kutanöz sessiz period (KSP) iletim çalışması yapıldı. Vitiligo şiddeti vitiligo alan skorlama indeksi ile değerlendirildi. Bulgular: Üst ve alt ekstremitelerin KSP distal latans ve süre değerleri iki grupta benzerdi (vitiligo ve kontrol). Vitiligo hastalarında hastalığın şiddeti ve süresi ile üst ve alt ekstremitelerin KSP değerleri arasında ilişki saptanmadı. Sonuç: Bu çalışmanın, vitiligonun her bir: miyelinli A delta lifleri ve küçük lifler olan demiyelinize C lifleri üzerindeki etkilerini gözlemlememize izin verdiği için değerli olduğunu düşünmekteyiz.

Anahtar Kelimeler:

kutanöz sessiz period; vitiligo; ince lif nöropatisi

Thin Fiber Neuropathy Associated with Vitiligo

Objective: This study is designed to detect thin fiber neuropathy, if any with patients who had vitiligo and had normal standard nerve conduction studies. Matherials and Methods: This case - control study was conducted between March 2016-June 2016 in ENMG laboratory of our neurology clinic. Amoung 123 vitiligo patients, 40vitiligo patients between ages 18-60 without evident neuropathy by standard nerve conduction studies were included in this study. Furthermore 40 healthy individuals without vitiligo or any neuropathy with matching age and gender were included in this study. All participants divided into two groups (vitiligo and control groups). Demographic data were recorded with weight, height, body mass index (BMI) data of participants. Cutaneous silent period conduction study was performed in median and sural nerves to evaluate small fiber conduction.Results: CSP duration and distal latency measurements abductor pollicis braves muscle on the upper extremity and tibialis anterior muscle on the lower extremity were similar in both CTS and control groups. Our findings show no association with vitiligo and small fiber neuropathy, Conclusion: We suppose that this study is valuable for allowing us to observe the effects of vitiligo on each: myelinated A delta fibers and demyelinated C fibers, which are small fibers.

Keywords:

cutaneous silent period; vitiligo; thin fiber neuropathy,

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