Çağrı Zorlu, Cemal Köseoğlu

Ortalama Trombosit Hacmi Koroner Arter Ektazisinde Düşüktür!

Amaç Koroner arter ektazi (KAE), bir koroner arterin bir segmentinin bitişiğindeki segmente göre en az 1.5 katı genişlemesi olarak tanımlanır. Birçok çalışma, ortalama trombosit hacmi (OTH) ile kardiyovasküler hastalıklar arasındaki ilişkiyi göstermiştir. Ancak çalışmaların sonuçları farklı olup kafa karıştırıcıdır. Bu nedenle OTH ile KAE ilişkisini araştırmayı amaçladık. Gereç ve Yöntemler Koroner arterleri normal 90 hasta ve KAE’ li 70 hasta çalışmaya dahil edildi. Anjiyografiden önce rutin kan ve biyokimyasal parametreler çalışıldı. Sürekli değişkenler için gruplar arasındaki farklar t-testi veya Mann-Whitney U testi ile analiz edildi. P

Mean Platelet Volume is Lower in Coronary Artery Ectasia!

Objective Coronary artery ectasia (CAE) are defined as the dilation of a segment of a coronary artery at least 1.5 times the adjacent segment. Several studies have shown the associationbetween mean platelet volume (MPV) and cardiovascular diseases. But the results are different. For this reason, we aimed to investigate the association of MPV with CAE.Materialsand Methods90 patients with normal coronary arteries and 70 patients with CAE were included. Routine blood and biochemical parameters were measured before the arteriography.Differences between groups for continuous variables were analyzed with t- test or Mann-Whitney U test. P values < 0.05 were considered significant.Results Baseline patient demographics, including age and clinical risk factors, were similar between the groups. Compared to the control group, MPV levels were significantly lowerin the CAE group (8.84 ± 1.71fL vs. 10.43 ± 1.34, p < 0.001). MPV level of < 9,5 fL showed sensitivity , specificity value of 95%, 80%; area under the curve= 0.943, 95% CI,0.906–0.980) for the prediction of CAE.Conclusion The present study suggests that MPV may decrease in patients with CAE.

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