Palyatif Bakım Hastalarında Psikososyal Semptomların Yönetimi

Modern palyatif bakım, görece olarak tıbbın ihmal ettiği ileri evre hastalığı olan bireylerin ve ailelerinin fiziksel ve psikolojik ıstırabına yanıt olarak ortaya çıkmıştır. Hastaların fiziksel semptomlarını hafifletmek için geliştirilen sistematik yaklaşımlarda ciddi ilerlemeler kaydedilmiş olmasına rağmen psikolojik semptomların yönetiminde alınan yol henüz yeterli değildir. Diğer taraftan psikolojik semptomların hafifletilmesine yönelik girişimler de rutin palyatif bakıma dahil edilememiş ve rastlantısal olarak uygulanmaktadır. Psikolojik bakımın bu görece ihmali, modern tıbbın tüm branşlarını kapsayan önemli bir sorundur. Bunun nedeni yaşamı sınırlayan bir hastalık durumunda gelişen psikolojik/ psikiyatrik semptomların hem hasta yakınları hem de sağlık çalışanları tarafından normal kabul edilmesi, empati içeren girişimlerin profesyoneller için zahmetli, kazanılması ve öğrenilmesi zor ve pahalı, ancak alıcılar için belki de tüm tıbbi girişimlerin içinde en ucuzu olmasıdır. Bu anlamda bakıldığında genel olarak psikolojik girişimler biyoloji ve teknolojiyi içeren girişimlerden daha az değerli olma eğilimindedir. Son on yılda palyatif bakım alan hasta ve ailelerinin psikososyal gereksinimlerine yönelik uygulanan girişimlerin etkinliğine dair kanıtlar da artış göstermektedir. Bu derlemede palyatif bakım hastalarına yönelik olarak gerçekleştirilen psikolojik girişimlerin etkinliğine dair kanıtların incelenmesi amaçlanmıştır.

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  • 1. Rodin G, An E, Shnall J, Malfitano C. Psychological interventions for patients with advanced disease: implications for oncology and palliative care. Journal of Clinical Oncology, 2020;38(9), 885-904.
  • 2. Maddock C, Pariante CM. How does stress affect you? An overview of stress, immunity, depression and disease. Epidemiol Psichiatr Soc. 2011;10:153–62.
  • 3. Spiegel D, Giese-Davis J. Depression and cancer: mechanisms and disease progression. Biol Psychiatry. 2003;54:269–82.
  • 4. Strine TW, Mokdad AH, Dube SR, Balluz LS, Gonzalez O, Berry JT, et al. The association of depression and anxiety with obesity and unhealthy behaviors among community-dwelling US adults. Gen Hosp Psychiatry. 2008;30:127–37.
  • 5. Wang, YH, Li JQ, Shi JF, Que JY, Liu JJ, Lappin JM, ... & Bao YP. Depression and anxiety in relation to cancer incidence and mortality: a systematic review and meta-analysis of cohort studies. Molecular Psychiatry, 2020;25(7), 1487-1499.
  • 6. Kruk J, Aboul-Enein BH, Bernstein J, Gronostaj M. Psychological stress and cellular aging in cancer: a meta-analysis." Oxidative medicine and cellular longevity 2019; 2019;1-23
  • 7. Singer S, Das-Munshi J, Brähler E. Prevalence of mental health conditions in cancer patients in acute care—a meta-analysis. Annals of oncology, 2010;21(5), 925-930.
  • 8. Mitchell AJ, Chan M, Bhatti H, et al. Prevalence of depression, anxiety, and 
adjustment disorder in oncological, haematological, and palliative-care set- tings: a meta-analysis of 94 interview-based studies. Lancet Oncol 2011; 12:160 – 174.
  • 9. Kaya F, Daştan N, Buzlu S, Distres. İçinde: Can G, Ed. Kanser Hastasında Palyatif Bakım. İstanbul: Nobel Tıp Kitapevi, 2017. s. 157-177.
  • 10. Von Blanckenburg P, Leppin N. Psychological interventions in palliative care. Current opinion in psychiatry, 2018;31(5), 389-395.
  • 11. Fu L, Yang Y, Hu Y, Lu Z, Zhang X, Huang M, Huang Z. (2021). Distress management in cancer patients: Guideline adaption based on CAN-IMPLEMENT. International Journal of Nursing Sciences, 2021
  • 12. Holtom N, Barraclough J. Is the Hospital Anxiety and Depression Scale (HADS) useful in assessing depression in palliative care?. Palliative Medicine, 2000;14(3), 219.
  • 13. Vehling S, Gerstorf D, Schulz‐Kindermann F, Oechsle K, Philipp R, Scheffold K, Lo C. The daily dynamics of loss orientation and life engagement in advanced cancer: a pilot study to characterise patterns of adaptation at the end of life. European journal of cancer care, 2018; 27(4),12842.
  • 14. Fulton J, Le Blanch T, Cutson T. Integrated outpatient palliative care for patients with advanced cancer: a systematic review and meta-analysis. Palliative medicine, 2019; 33(2) 123-134.
  • 15. Okuyama T, Akechi T, Mackenzie L, Furukawa TA. Psychotherapy for depression among advanced, incurable cancer patients: a systematic review and meta-analysis. Cancer Treat Rev 2017; 56:16–27.

  • 16. Oberoi S, Yang J, Woodgate RL, Niraula S, Banerji S, Israels SJ, Zarychanski R. Association of mindfulness-based interventions with anxiety severity in adults with cancer: a systematic review and meta-analysis. JAMA network open, 2020; 3(8), 2012598-2012598.
  • 17. Zimmermann FF, Burrell B, Jordan J. The acceptability and potential benefits of mindfulness-based interventions in improving psychological well being for adults with advanced cancer: a systematic review. Complement Ther Clin Pract, 2018; 30:68 – 78.
  • 18. Chambers SK, Occhipinti S, Foley E, Clutton S, Legg M, Berry M, Smith DP. Mindfulness-based cognitive therapy in advanced prostate cancer: a randomized controlled trial. Journal of Clinical Oncology, 2017;35(3), 291-297.
  • 19. Milbury K, Engle R, Liao ZX, Tsao AS, Owens A, Bruera E, Cohen L. Couple-based mind-body intervention for patients with metastatic lung cancer and their spouses, 2017;35(31),179-186.
  • 20. Hassan S, Bennett K, Serfaty M. Delivering cognitive behavioural therapy to & advanced cancer patients: A qualitative exploration into therapists’ experiences within a UK psychological service. Clin Psychol Psychother, 2018; 00:1-10.

  • 21. Vos J, Vitali D. The effects of psychological meaning-centered therapies on quality of life and psychological stress: A metaanalysis. Palliative & supportive care, 2018;16 (5):608-632.
  • 22. Dietrich N, Estradé A, Cruzado JA. Efficacy of Meaning-Centered Psychotherapy in adult patients with advanced cancer: A systematic review and meta-analysis. Psicooncologia, 2021;18(2),227-244
  • 23. Torres-Blasco N, Castro-Figuero E, Garduño-Ortega O, Costas-Muñiz R. Cultural Adaptation and Open Pilot of Meaning-Centered Psychotherapy for Puerto Rican Patients with Advanced Cancer. Science, 2020; 8(4), 100-107.
  • 24. Kang KA, Han SJ, Lim YS, Kim SJ. Meaning-centered interventions for patients with advanced or terminal cancer: a meta-analysis. Cancer Nursing, (2019);42(4), 332-340.
  • 25. Rosenfeld B, Cham H, Pessin H, Breitbart W. Why is Meaning-Centered & Group Psychotherapy (MCGP) effective? Enhanced sense of meaning as the mechanism of change for advanced cancer patients. Psychooncology 2018;
  • 26. Rosenfeld B, Cham H, Pessin H, Breitbart W. Why is M eaning‐C entered G roup P sychotherapy (MCGP) effective? Enhanced sense of meaning as the mechanism of change for advanced cancer patients. Psycho‐Oncology, 2018; 27(2), 654-660.
  • 27. Edwards A, Pang N, Shiu V, Chan C. The understanding of spirituality and the potential role of spiritual care in end-of-life and palliative care: a meta-study of qualitative research. Palliative medicine, 2010;24(8), 753-770.
  • 28. Xing L, Guo X, Bai L, Qian J, Chen J. Are spiritual interventions beneficial to patients with cancer?: A meta-analysis of randomized controlled trials following PRISMA. Medicine, 2018; 97(35),1-11
  • 29. Erişen M, Karaca S,. Manevi bakım ve hemşirelik. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 2017; 6.3: 184-190.
  • 30. Cuevas PE, Davidson P, Mejilla J. Dignity therapy for end-of-life care patients: a literature review. Journal of Patient Experience, 2021;8:1-12
  • 31. Martínez M, Arantzamendi M, Belar A, Carrasco JM, Carvajal A, Rullán M, Centeno C. Dignity therapy’, a promising intervention in palliative care: A comprehensive systematic literature review. Palliative medicine, 2017; 31(6), 492-509.
  • 32. Grijo L, Tojal C, Rego F. Effects of dignity therapy on palliative patients’ family members: A systematic review. Palliative & Supportive Care, 2021; 1-10.
  • 33. Guo Q, Chochinov HM, McClement S, et al. Development and evaluation of the dignity talk question framework for palliative patients and their families: a mixed-methods study. Palliat Med 2018; 32:195 – 205.
48.
  • 34. Ho AHY, Car J, Ho MR. A novel Family Dignity Intervention (FDI) for enhancing and informing holistic palliative care in Asia: study protocol for a randomized controlled trial. Trials 2017; 18:1-12.

  • 35. Wang CW, Chow AY, Chan CL. The effects of life review interventions on spiritual well-being, psychological distress, and quality of life in patients with terminal or advanced cancer: a systematic review and meta-analysis of randomized controlled trials. Palliative medicine, 2017;31(10), 883-894
  • 36. Garcia-Rueda N, Valcarcel AC, Saracibar-Razquin M, Solabarrieta MA. The experience of living with advanced-stage cancer: A thematic synthesis of the literature. European Journal of Cancer Care, 2016;25, 551-569.
  • 37. Bradley N, Lloyd‐Williams M, Dowrick C. Effectiveness of palliative care interventions offering social support to people with life‐limiting illness-A systematic review. European journal of cancer care, 2018;27(3),128-37.
  • 38. Nipp RD, El-Jawahri A, Fishbein JN, Eusebio J, Stagl JM, Gallagher ER, Temel JS. The relationship between coping strategies, quality of life, and mood in patients with incurable cancer. Cancer, 2016; 122, 2110-2116.
  • 39. Epstein RM, Duberstein PR, Fenton JJ, Fiscella K, Hoerger M, Tancredi DJ, Kravitz RL. Effect of a patient-centered communication intervention on oncologist-patient communication, quality of life, and health care utilization in advanced cancer: the VOICE randomized clinical trial. JAMA Oncology, 2017;3(1), 92-100.
  • 40. Donker T, Griffits KM, Cuijpers P, Cristensen H. Psychoeducation for depression, anxiety and psychological distress: a meta-analysis. BMC Medicine 2009; (7):79-88. 

  • 41. Hoerger M, Perry LM, Gramling R, Epstein RM, Duberstein PR. Does educating patients about the Early Palliative Care Study increase preferences for outpatient palliative cancer care? Findings from Project EMPOWER. Health Psychology, 2017; 36(6), 538–548
  • 42. Cheng Q, Xu B, Ng MS, Duan Y, So WK. Effectiveness of psychoeducational interventions among caregivers of patients with cancer: A systematic review and meta-analysis. International Journal of Nursing Studies, 2021;104162.
  • 43. Wang Y, Lin Y, Chen J, Wang C, Hu R, Wu Y. Effects of Internet-based psycho-educational interventions on mental health and quality of life among cancer patients: a systematic review and meta-analysis. Supportive Care in Cancer, 2020; 28(6), 2541-2552.
  • 44. Candy B, Armstrong M, Flemming K, Kupeli N, Stone P, Vickerstaff V, Wilkinson S. The effectiveness of aromatherapy, massage and reflexology in people with palliative care needs: a systematic review. Palliative medicine, 2020; 34(2), 179-194.
  • 45. Zeng YS, Wang C, Ward KE, Hume AL. Complementary and alternative medicine in hospice and palliative care: a systematic review. Journal of pain and symptom management, 2018;56(5), 781-794.
  • 46. Hsu CH, Chi CC, Chen PS, Wang SH, Tung TH, Wu SC. The effects of aromatherapy massage on improvement of anxiety among patients receiving palliative care: A systematic review of randomized controlled trials. Medicine, 2019;98(9).
  • 47. Armstrong M, Flemming K, Kupeli N, Stone P, Wilkinson S, Candy B. Aromatherapy, massage and reflexology: a systematic review and thematic synthesis of the perspectives from people with palliative care needs. Palliative medicine, 2019; 33(7), 757-769.
  • 48. Wu X, Chung VC, Hui EP, Ziea ET, Ng BF, Ho RS. Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews. Sci Rep. 2015;5:167-76.
  • 49. Birch S, Bovey M, Alraek T, Robinson N, Kim TH, Lee MS. Acupuncture as a treatment within integrative health for palliative care: a brief narrative review of evidence and recommendations. The Journal of Alternative and Complementary Medicine, 2020; 26(9), 786-793.