Coronavirus: Genel Özellikler ve Güncel Yaklaşım

İlk defa Aralık 2019’da Çin’in Wuhan Şehrinde ortaya çıkan pnömoni vakalarından izole edilen ve Coronaviridae ailesinden olduğu belirlenen virus “severe acute respiratory syndrome coronavirus-2; SARS-CoV-2” olarak adlandırılmıştır. Diğer coronaviruslar gibi zoonotik kaynaklı olan SARS-CoV-2’nin genetik analizleri, yarasa coronavirus popülasyonları ile aynı kökene sahip olduğunu göstermektedir. İnsanlar ve yarasalar arasında genellikle sınırlı bir temas olduğundan, virusun insanlara bulaşmasının, insanlar ile temas olasılığı daha fazla olan başka bir hayvan türü yoluyla gerçekleşmesi daha olasıdır. Bu ara konak, evcil bir hayvan, vahşi bir hayvan veya evcilleştirilmiş bir vahşi hayvan olabilir, ancak henüz tanımlanmamıştır. Bu makalede coronavirusların yapısal ve epidemiyolojik özellikleri incelenerek tüm dünyayı etkisi altına alan SARS-CoV-2’ye dair güncel gelişmeler değerlendirilmiştir.

Coronavirus: General Features and Current Approach

The virus, which was isolated from the pneumonia cases in Wuhan City in Hubei Province of China for the first time in December 2019 and determined to be from the Coronaviridae family, was called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Genetic analysis of SARS-CoV-2, originating from zoonotic like other coronaviruses, indicates that it has the same origin as bat coronavirus populations. Since there is usually limited contact between humans and bats, the transmission of the virus to humans is more likely to occur through another animal species that is more likely to be contacted. This intermediate host can be a pet, a wild animal or a domesticated wild animal, but has not yet been identified. In this article, structural and epidemiological features of coronaviruses are examined and current developments about SARS-CoV-2, which take over the world, are evaluated.

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