BAZI BİYOMALZEMELERİN DOKU KAPATMA YAPIŞTIRICISI OLARAK KULLANIMININ DEĞERLENDİRİLMESİ: İLK SONUÇLAR

Amaç: Entellan gibi sentetik tutkallar, dokuları uzun su re korumak ve mikroskop altında daha parlak ve da-ha net go ru nmelerini sag lamak için kullanılır. Bu madde dokuya damlatıldıktan sonra u zerine bir lamel yerleşti-rilerek kapatılır. Sentetik tutkallar, metakrilat ve tu rev-leri gibi zararlı kimyasallar içerir. Sentetik polimerik yapıştırıcıların çevre ve kullanıcı u zerindeki toksik etki-leri bilinmektedir. Materyal ve metod: Bu çalışmada tutkal karışımları elde etmek için hayvan ve bitki kaynaklı biyomalzemeler kullanıldı. Dog al ve sag lıklı bir tutkal u retmek için polar ço zu cu , sitrik asit, amonyak, hidroklorik asit, nano silika ve karanfil yag ı gibi biyomalzemeler kullanıldı. Mikros-kop go ru ntu leri, aynı dokuların biyomalzeme içeren karışımlarla kapatılmasıyla elde edildi. Referans tutkal maddesi olarak entellan kullanıldı. Bulgular: Entellan kullanılarak kapatılan dokulara go re bazı karışımlarda aynı go ru ntu kalitesi ve kapanma mukavemeti elde edildi. Sonuç: Bu ilk çalışma, biyomateryal içeren dog al tutkal-ların diş ve tıbbi laboratuvarlarda ve dig er amaçlarla kullanımını arttırmak için bir adım oluşturacaktır. Çu n-ku keskin kokuları veya toksik o zellikleri yoktur ve çev-re dostudurlar.

EVALUATION OF THE USING SOME BIOMATERIALS AS TISSUE CLOSING ADHESIVES AGENT: FIRST RESULTS BAZI BİYOMALZEMELERİN DOKU KAPATMA YAPIŞTIRICISI OLARAK KULLANIMININ DEĞERLENDİRİLMESİ: İLK SONUÇLAR

Purpose: Synthetic glues like entellan are used for long-term preservation of tissues and procurement of brigh-ter and clearer apperance under microscope. Generally, synthetic glues contain harmful chemicals such as met-hacrylate and derivatives. The toxic effects of synthetic polymeric adhesives on the environment and the wea-rer are known.Material and methods: In this study, biomaterials of animal and plant origin were used to obtain glue mixtu-res. Polar solvent, citric acid, ammonia, hydrochloric acid, nano silica and clove oil were used in order to pro-duce a more natural and healthy glue. Microscope ima-ges were obtained by closing the same tissues with mixtures containing biomaterials. Entellan was used as reference glue substance.Results: The same image quality and closure strength were obtained with some mixtures according to tissues closed using entellan.Conclusion: This first study will constitute a step to increase the use of natural glues containing biomateri-als in dental and medicinal laboratories and other pur-poses since they have no pungent smell or toxic proper-ties as well as being environmentally friendly.

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