An Uncommon Cause of MINOCA: Mad Honey Poisoning

An Uncommon Cause of MINOCA: Mad Honey Poisoning

Consumption of grayanotoxin-containing honey that is produced from flowers of the Rhododendron family causes mad honey intoxication, in other words grayanotoxin poisoning (1). This flower family grows in Japan, Nepal, Brazil, parts of North America, and the eastern Black Sea region of Turkey. Grayanotoxin is accountable for clinical presentation. Dose-dependent, grayanotoxin causes different clinical conditions from dizziness, hypotension, and bradycardia to impaired consciousness, syncope, atrioventricular block, and asystole due to vagal stimulation. (2). But consumption of mad honey is a rare cause of acute coronary syndrome. Herein, we present the case of a 49-year-old man who presented to hospital with dizziness whose electrocardiogram (ECG) shows sign of acute inferior myocardial infarction after consumption of mad honey.

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  • 3. Shrestha et al. Cardiovascular, psychiatric, and neurological phenomena seen in mad honey disease: A clinical case report, Clin Case Rep. 2018;6:2355–2357
  • 4. Karabag T, et al. Myocardial infarction related with mad honey, Korean J Intern Med 2015;30:540-542
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