4B Biyobaskı Çalışmalarında Güncel Yenilikler

Dört boyutlu (4B) biyobaskı tekniklerinin biyofabrikasyon teknolojilerinin geleceği olduğu düşünülmektedir. Elektrik, sıcaklık, nem, manyetik vs. gibi uyarıcılar aracılığı ile şekil değiştiren akıllı malzemeler kullanılarak ortaya çıkartılmış olan 4B biyobaskı tekniği, 3B biyolojik materyallerden oluşmuş ve zamanla şekil değiştirebilen yapılar üretilebilmektir. Bu mini derlemede bu alanda son yıllarda ortaya konmuş olan pek çok akıllı malzeme ve bunların önemleri açıklanmıştır. Akıllı malzemelerin ve 4B biyoyazıcı tekniklerinin çok yakın bir gelecek içerisinde yumuşak robotik sistemlerin tasarımlarında ve hiyerarşik, kompleks, kalın ve damar dokusu eklemlenmiş doku yapılarının tasarımlanmasında aşırı derecede önem kazanacağı düşünülmektedir.

Recent Advances in 4D Bioprinting

Four-dimensional (4D) bioprinting, is generally accepted as the future of biofabrication technologies. 4D bioprinting develops dynamic and 3D based biological materials which can shift their shapes or alter their behaviors when several stimulants like electricity, temperature, humidity, magnetic etc. are applied. In this review, we highlighted the important aspects of several smart materials for 4D bioprinting that have been used recently for biofabrication researches. It is believed that in immediate future, smart materials and 4D Bioprinting techniques will have an excessive importance for designing of soft robotic systems and architecture of hierarchial, compex, thick and vascularized tissue structures

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