Önder OTLU, Tuğba Raika KIRAN, Ercan KARABULUT, Aysun BAY KARABULUT

Kuru kayısılardaki kükürt miktarının serum oksidatif stres parametleri üzerine etkisi

Kayısı, dünyanın farklı bölgelerinde yetiştirilebilen ve ticari öneme sahip bir meyvedir. Kayısılar güneşte veya depolanma süresini uzatmak amacıyla kükürtle muamele edilerek kurutulmaktadır. Özellikle Avrupa Birliği ülkeleri ve ülkemizde kuru kayısıda bulunması gereken kükürt miktarı 2000 mg/L olarak belirlenmiştir ve bu miktar azaltılmak istenmektedir. Çalışmanın amacı, yüksek ve düşük kükürt içerikli kayısılarla beslenmenin serum oksidatif stres parametreleri üzerine etkilerini karşılaştırmaktır. Toplamda 84 adet Wistar albino rat, gün kurusu kayısı ve farklı miktarda kükürt içeren kuru kayısıların kullanıldığı yemlerle 12 hafta boyunca beslendi. Ratların serum Total antioksidan seviye, Total oksidan seviye, Malondialdehit ve Glutatyon seviyeleri ölçüldü. En yüksek total antioksidan seviye gün kurusu kayısı ile beslenen grupta, en düşük total antioksidan seviye ise 3000 mg/L grubunda gözlemlenmiştir. Malondialdehit seviyelerinde sadece 1000 mg/L grubunda, Glutatyon seviyelerinde ise 1000 mg/L, 2000 mg/L ve 3000 mg/L gruplarında anlamlı artışlar görülmüştür.

Anahtar Kelimeler:

Kükürtlü kayısı, Oksidatif stres, Rat, Serum

Effect of sulfur amount in dry apricot on serum oxidative stress parameters

Apricot is one of the important fruit that can be grown in many parts of the world. The apricots are dried in the sun or by treatment with sulfur to prolong the storage time. In many European countries and in our country, the amount of sulfur required in dried apricots is 2000mg/L and this amount is likely to drop down. The aim of this study is to compare the effects of feeding with high and low sulfur bearing apricot on serum oxidative stress parameters. In total, 84 Wistar albino rats were fed for 12 weeks with dried apricots containing different amounts of sulfur or sun-dried apricots. Serum total antioxidant level, total oxidant level, malondialdehyde and glutathione levels of the rats were measured. The highest total antioxidant level was observed in the group fed with sun dried apricot, while the lowest total antioxidant level was observed in the 3000 mg/L group. Malondialdehyde levels increased only in 1000 mg/L group, while glutathione levels were significantly increased in 1000 mg/L, 2000 mg/L and 3000 mg/L groups.

Keywords:

Sulfur dried apricot, Oxidative stress, Rat, Serum,

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