Pınar Canizci ERDEMLİ, Pınar TURHAN, Cengiz CANDAN

Karaciğer kist hidatik hastalığı sonrası gelişen tübülointerstisyel nefrite ikincil akut böbrek hasarı

Renal hidatik hastalık literatürde iyi tanımlanmıştır ve pekçok çalışma mevcuttur. Bununla birlikte doğrudan invazyon olmaksızın böbrek hasarı gelişimi oldukça nadir bir durumdur. Bu sunumda hepatik kist hidatiği olan hastada tubulointerstisyel nefrite ikincil akut böbrek hasarı gelişen bir vaka bildirilmiştir. Hasta albendazol ve perkütan aspirasyon injeksiyon ve reaspirasyon girişimi ile tedavi edilmiştir. Halen oral albendazol tedavisi ile izlenen hastanın bulguları izlemde düzelmiştir.

Acute kidney injury secondary to tubulointerstitial nephritis due to hepatic hydatid disease in a pediatric patient

Renal hydatid disease is well defined, and many studies are present in the literature. Howewer, renal injury without direct renal invasion is a less well-known subject. Here is the report of a patient with hepatic hydatid cyst who presented with acute renal failure secondary to tubulointerstitial nephritis. The patient was treated with the combination of albendazole, and percutaneous aspiration, injection, and re-aspiration therapy. The patient is now on oral albendazole therapy and doing well on follow-up.

PDF

___

1. McManus DP, Zhang W, Li J, Bartley PB. Echinococcosis. Lancet 2003;362:1295-1304. https://doi.org/10.1016/ S0140-6736(03)14573-4
2. Angulo JC, Sanchez-Chapado M, Diego A, Escribano J, Tamayo JC, Martin L. Renal echinococcosis: Clinical study of 34 cases. J Urol 1997;157:787-794. https://doi. org/10.1016/s0022-5347(01)65041-9
3. Howell M, Sebire NJ, Marks SD, Tullus K. Biopsy- proven paediatric tubulointerstitial nephritis. Pediatr Nephrol 2016;31:1625-1630. https://doi.org/10.1007/ s00467-016-3374-9
4. Altay M, Ünverdi S, Altay FA, et al. Renal injury due to hepatic hydatid disease. Nephrol Dial Transplant 2010;25:2611-2615. https://doi.org/10.1093/ndt/gfq092
5. Vialtel P, Chenais F, Desgeorges P, Couderc P, Micouin C, Cordonnier D. Membranous nephropathy associated with hydatid disease. N Engl J Med 1981;304:610-611. https://doi.org/10.1056/NEJM198103053041016
6. Sanchez Ibarrola A, Sobrini B, Guisantes J, et al. Membranous glomerulonephritis secondary to hydatid disease. Am J Med 1981;70:311-315. https://doi. org/10.1016/0002-9343(81)90766-x
7. Covic A, Mititiuc I, Caruntu L, Goldsmith DJ. Reversible nephrotic syndrome due to mesangiocapillary glomerulonephritis secondary to hepatic hydatid disease. Nephrol Dial Transplant 1996;11:2074-2076. https://doi.org/10.1093/oxfordjournals.ndt.a02710
8. Gelman R, Brook G, Green J, Ben-Itzhak O, Nakhoul F. Minimal change glomerulonephritis associated with hydatid disease. Clin Nephrol 2000;53:152-155.
9. Nalcacioglu H, Tekcan D, Genc G, et al. A rare cause of nephrotic syndrome in a 14-year-old boy: Answers. Pediatr Nephrol 2013;28:1069-1071. https://doi. org/10.1007/s00467-012-2282-x
10. Barsoum RS. Tropical parasitic nephropathies. Nephrol Dial Transplant 1999;14:79-91. https://doi.org/10.1093/ ndt/14.suppl_3.79
11. Nickavar A. Hydatid disease and tubulointerstitial nephritis. Pediatr Nephrol 2011;26:1171-1172. https:// doi.org/10.1007/s00467-011-1852-7
12. Aziz F, Pandya T, Patel HV, et al. Nephrotic presentation in hydatid cyst disease with predominant tubulointerstital disease. Int J Nephrol Renovasc Dis 2009;2:23-26.