Hazar HARBALIOĞLU, Caner TURKOGLU, Taner ŞEKER, Alaa QUİSİ, Omer GENC, Gökhan ALICI, Samir ALLAHVERDİYEV, Ahmet Oytun BAYKAN, Mustafa GÜR

Akut miyokart enfarktüsü olan hastalarda sorumlu lezyonun bifurkasyon lezyon olma sıklığı ve seçilen tedavi stratejisinin erken ve geç dönem sonuçlara etkisi

Background: Although, there are several studies comparing single and two-stent techniques in patients with bifurcation lesions, evidence in patients presenting with myocardial infarction (MI) is still insufficient. We aimed to assess the short and long term outcomes of provisional and two-stent techniques of bifurcation lesions in patients with ACS. Methods: 2992 patients with MI who underwent percutaneous coronary intervention (PCI) were enrolled in the present study. Of 2992 patients, 385 patients with MI had bifurcation lesions. The Synergy between PCI with TAXUS™ and Cardiac Surgery (SYNTAX) score, pre-PCI Thrombolysis in Myocardial Infarction (TIMI) flow, post-PCI TIMI flow, duration of procedure, angiographic features, post-PCI side branch loss, 1- and 12-month mortality rates were noted. Results: 169 (43.9 %) patients had ST segment elevation MI, whereas 216 (56.1%) patients had non-ST segment elevation MI. 355 (92.2%) patients underwent provisional stenting and 30 (7.8%) patients underwent two-stent technique. Side branch loss was observed in 40 patients (11.2 %) in the provisional group and 1 patient (3.3%) in the two-stent group (p=0.2). Compared to provisional group, durations of angiography and revascularization in two-stent group were significantly longer (p<0.001 and p<0.001). Both 1-month and 12-month mortality rates were similar in provisional and two-stent groups (4.2% vs. 3.3%, p=0.8 and 11.5% and 13.3%, p=0.7; respectively). Conclusion: In patients presenting with ACS and bifurcation lesions, procedural success, side branch loss, as well as short and long term mortality were similar in both provisional and two-stent techniques.

Anahtar Kelimeler:

Akut koroner sendrom, bifurkasyon, revaskülarizasyon, yan dal kaybı, mortalite

Incidence of bifurcation coronary lesion as a culprit lesion in patients with acute myocardial infarction: impact of treatment strategy on short and long term outcomes

AbstractPurpose: Although, there are several studies comparing single and two-stent techniques in patients withbifurcation lesions, evidence in patients presenting with myocardial infarction (MI) is still insufficient. We aimedto assess the short and long term outcomes of provisional and two-stent techniques of bifurcation lesions inpatients with ACS.Materials and methods: 2992 patients with MI who underwent percutaneous coronary intervention (PCI) wereenrolled in the present study. Of 2992 patients, 385 patients with MI had bifurcation lesions. The Synergybetween PCI with TAXUS™ and Cardiac Surgery (SYNTAX) score, pre-PCI Thrombolysis in MyocardialInfarction (TIMI) flow, post-PCI TIMI flow, duration of procedure, angiographic features, post-PCI side branchloss, 1- and 12-month mortality rates were noted.Results: 169 (43.9%) patients had ST segment elevation MI, whereas 216 (56.1%) patients had non-ST segmentelevation MI. 355 (92.2%) patients underwent provisional stenting and 30 (7.8%) patients underwent two-stenttechnique. Side branch loss was observed in 40 patients (11.2%) in the provisional group and 1 patient (3.3%)in the two-stent group (p=0.2). Compared to provisional group, durations of angiography and revascularizationin two-stent group were significantly longer (p<0.001 and p<0.001). Both 1-month and 12-month mortalityrates were similar in provisional and two-stent groups (4.2% vs. 3.3%, p=0.8 and 11.5% and 13.3%, p=0.7;respectively).Conclusion: In patients presenting with ACS and bifurcation lesions, procedural success, side branch loss, aswell as short and long term mortality were similar in both provisional and two-stent techniques.

Keywords:

Acute coronary syndrome, bifurcation, revascularization, side branch loss, mortality,

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