Engin OZAKİN, Volkan ERCAN, KADİR UĞUR MERT

Metoklopramide Bağlı Gelişen Kounis Sendromu Olgusu

Kounis sendromu, aşırı duyarlılık reaksiyonlarına sekonder kararsız vazospastik veya vazospastik olmayan anjinaya neden olan semptomlarla karakterizedir. Kounis tarafından 1991'de tanımlandıktan sonra bu sendrom, akut koroner sendromla ilişkili bir dizi mast hücresi aktivasyon bozukluğunu içerir. Çoklu ilaçlara verilen reaksiyonlar, balık, domates, meyve, arı sokması zehirli sarmaşık, engerek zehiri, kabuklu deniz ürünleri gibi gıdaları ve koroner stentleri içeren birçok tetikleyici faktör vardır. Olgumuzda, bulantı için metoklopramid uygulandıktan sonra Kounis sendromu gelişen koroner risk faktörü veya aile öyküsünde koroner arter hastalığı bulunmayan 71 yaşında erkek hastayı sunuyoruz.

Anahtar Kelimeler:

Kounis, miyokard enfarktüsü, allerji, metoklopramid

A Case with Kounis Syndrome After the Administration of Metoclopramid

Kounis syndrome is characterized by a symptoms that cause unstable vasospastic or non-vasospastic angina secondary to a hypersensitivity reactions. After identification by Kounis in 1991, this syndrome includes a series of mast cell activation disorders associated with acute coronary syndrome. There are many triggering factors, including reactions to multiple medications, foods such as fish, tomato, fruits, bee stings poison ivy, viper venom, shellfish and coronary stents. We report the case of 71-year-old man with no coronary risk factors or family history of coronary artery disease, who developed Kounis syndrome after the administration of metoclopramide for nausea.

Keywords:

Kounis, myocardial infarction, allergy, metoclopramide,

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