Deneysel Temas Yanık Modellerinde Sıklıkla Kullanılan Metal Pabuçların Temas Yüzeylerinin Gerçek Sıcaklıklarının Araştırılması

Deneysel ve klinik çalışmalar ışığında 20. yy’ın ikinci yarısından sonra yanık hastalarına yaklaşımda gelişmeler ve değişiklikler olmuştur. Bu noktada deneysel ve klinik çalışmaların rolü büyüktür. Gerek fizyopatolojiyi gerekse tedavi alternatiflerini değerlendirmek amacıyla çok çeşitli haşlanma ve temas yanık modelleri tanımlanmıştır. Ancak deneysel temas yanığı çalışmalarında altın standardı arayış devam etmektedir. Temas yanık modelinde sıcaklık, uygulama kuvveti ve süresi yanık derinliğinde belirleyici faktörlerdir. Literatürde yakıcı pabuçların dört ana metalden (bakır, pirinç, alüminyum ve paslanmaz çelik) yapıldığı anlaşılmaktadır. Ancak metallerin ısıl iletkenliğinin farklı olması nedeniyle gerçek zamanlı temas yüzeyi sıcaklığının özellikle ön ısıtmalı modellerde tahmin edildiği gibi olmadığı düşüncesindeyiz. Bu noktadan hareketle çalışmada, farklı metallerden üretilmiş yakıcı pabuçların gerçek zamanlı temas yüzeyi sıcaklığının karşılaştırılması amaçlanmıştır.

Anahtar Kelimeler:

yanık, sıcaklık, deneysel, metal

Comparison of Real-Time Contact Surface Temperature of Metal Bars That Are Frequently used ın Experimental Contact Burn Models

In the light of experimental and clinical studies, during the second half of 20th century approach to the burns have developed and changed. For understanding the pathophysiology or respond to treatment modalities, different types of scalding and contact burn models have been defined. However, studies are going on to achieve the gold standard. In contact burn models, temperature (T), exposure time and weight force applied while creating the wound are the determinant variables for the depth of burn wound. According to literature, four main types of metals, copper, aluminum, brass and stainless-steel were used for fabricating the burning bar (BB). And due to different thermal conductivity of metals, we believe that real-time contact surface T of burning bar is obscure whereas it could play an important role on the depth of burns. Hence, the aim of the study was to present the differences of real-time T of contact surface accordingly.

Keywords:

burns, standardization, experimental, meta,

PDF

___

References
1. Abdullahi A, Amini-Nik S, Jeschke MG. Animal models in burn research. Cell Mol Life Sci. 2014;71(17):3241-55.
2. Arda MS, Kocman AE, Soztutar E, Baksan B, Cetin C. A new apparatus for standardization of experimental burn models. Burns : journal of the International Society for Burn Injuries. 2017;43(6):1322-9.
3. Campelo AP, Campelo MW, Britto GA, Ayala AP, Guimaraes SB, Vasconcelos PR. An optimized animal model for partial and total skin thickness burns studies. Acta Cir Bras. 2011;26 Suppl 1:38-42.
4. Kim JY, Dunham DM, Supp DM, Sen CK, Powell HM. Novel burn device for rapid, reproducible burn wound generation. Burns : journal of the International Society for Burn Injuries. 2016;42(2):384-91.
5. Meyer TN, Silva ALd. A standard burn model using rats. Acta Cirurgica Brasileira. 1999;14(4):0
6. Singer AJ, Berruti L, Thode HC, McClain SA. Standardized burn model using a multiparametric histologic analysis of burn depth. Academic Emergency Medicine. 2000;7(1):1-6.
7. Singer AJ, McClain SA. A porcine burn model. Methods in molecular medicine. 2003;78:107-19.
8. Venter NG, Monte-Alto-Costa A, Marques RG. A new model for the standardization of experimental burn wounds. Burns : journal of the International Society for Burn Injuries. 2015;41(3):542-7.
9. Cai EZ, Ang CH, Raju A, Tan KB, Hing EC, Loo Y, et al. Creation of consistent burn wounds: a rat model. Arch Plast Surg. 2014;41(4):317-24.
10. Gaines C, Poranki D, Du W, Clark RA, Van Dyke M. Development of a porcine deep partial thickness burn model. Burns : journal of the International Society for Burn Injuries. 2013;39(2):311-9.
11. Kempf M, Cuttle L, Liu PY, Wang XQ, Kimble RM. Important improvements to porcine skin burn models, in search of the perfect burn. Burns : journal of the International Society for Burn Injuries. 2009;35(3):454-5.
12. Wang X KR. A review on porcine burn and scar models and their relevance to humans. Wound Practice and Research. 2010;18(1).
13. Sakamoto M, Morimoto N, Ogino S, Jinno C, Kawaguchi A, Kawai K, et al. Preparation of Partial-Thickness Burn Wounds in Rodents Using a New Experimental Burning Device. Ann Plast Surg. 2016;76(6):652-8.
14. Singh M, Nuutila K, Minasian R, Kruse C, Eriksson E. Development of a precise experimental burn model. Burns : journal of the International Society for Burn Injuries. 2016;42(7):1507-12.
15. Singer AJ, Taira BR, Anderson R, McClain SA, Rosenberg L. Does pressure matter in creating burns in a porcine model? Journal of burn care & research : official publication of the American Burn Association. 2010;31(4):646-51.
16. Cuttle L, Kempf M, Phillips GE, Mill J, Hayes MT, Fraser JF, et al. A porcine deep dermal partial thickness burn model with hypertrophic scarring. Burns : journal of the International Society for Burn Injuries. 2006;32(7):806-20.
17. Sevgi M, Toklu A, Vecchio D, Hamblin MR. Topical antimicrobials for burn infections - an update. Recent Pat Antiinfect Drug Discov. 2013;8(3):161-97.
18. Mortell A, Montedonico S, Puri P. Animal models in pediatric surgery. Pediatr Surg Int. 2006;22(2):111-28.