Meme Kanserinde Oksidatif Stresin Prognostik Değeri ve Önemi

Amaç: Meme kanseri hastalarında Total Antioksidan Status (TAS), Total Oksidan Status (TOS), Oksidatif Stres İndeks (OSI) düzeylerini araştırmak ve bunları sağlıklı kadınlarla karşılaştırmaktır.

Prognostic Value and Significance of Oxidative Stress in Breast Cancer

Objective: The aims of this study were to investigate Total Antioxidative Status (TAS), Total Oxidative Status (TOS), and Oxidative Stress Index (OSI) levels in breast cancer patients and compare them to levels in healthy women.

___

  • Özcan O, Erdal H, Çakırca G, Yönden Z. Oxidative stress and its impacts on intracellular lipids, proteins and DNA. J Clin Exp Invest. 2015;6(3):331-336. doi:10.5799/ahinjs.01.2015.03.0545
  • Altan N, Dinçel AS, Koca C. Diabetes mellitus ve oksidatif stres. Turk J Biochem. 2006;31:51-56.
  • Kim SY, Kim JW, Ko YS, Koo JE, Chung HY, Lee-Kim YC. Changes in lipid peroxidation and antioxidant trace elements in serum of women with cervical intraepithelial neoplasia and invasive cancer. Nutr Cancer. 2003;47(2):126-130. doi:10.1207/s15327914nc4702_3
  • Nayak SB, Yashwanth S, Pinto SM, Bhat VR, Mayya SS. Serum copper, ceruloplasmin, protein thiols and thiobarbituric acid reactive substance status in liver cancer associated with elevated levels of alpha-fetoprotein. Indian J Physiol Pharmacol. 2005;49(3):341-344.
  • Leung EY, Crozier JE, Talwar D, et al. Vitamin antioxidants, lipid peroxidation, tumour stage, the systemic inflammatory response and survival in patients with colorectal cancer. Int J Cancer. 2008;123(10):2460–2464. doi:10.1002/ijc.23811
  • Kundaktepe BP, Sozer V, Durmus S, et al. The evaluation of oxidative stress parameters in breast and colon cancer. Medicine (Baltimore). 2021;100(11):e25104. doi:10.1097/MD.0000000000025104
  • Rainis T, Maor I, Lanir A, Shnizer S, Lavy A. Enhanced oxidative stress and leucocyte activation in neoplastic tissues of the colon. Dig Dis Sci. 2007;52(2):526–530. doi:10.1007/s10620-006-9177-2
  • Srivastava DS, Mittal RD. Free radical injury and antioxidant status in patients with benign prostate hyperplasia and prostate cancer. Indian J Clin Biochem. 2005;20(2):162–165. doi:10.1007/BF02867419
  • Yang YW, Dai CM, Chen XH, Feng JF. The Relationship between serum trace elements and oxidative stress of patients with different types of cancer. Oxid Med Cell Longev. 2021;2021:4846951. doi:10.1155/2021/4846951
  • Huang Y, Sheu J, Lin T. Association between oxidative stress and changes of trace elements in patients with breast cancer. Clin Biochem. 1999;32:131-136. doi:10.1016/s0009-9120(98)00096-4
  • Rajizadeh A, Mozaffari-Khosravi H, Zavar-Reza J, Shiryazdi SM. Comparison of hematological parameters, iron levels, and oxidative stress in women with and without breast cancer: A case- control study. Med J Islam Repub Iran. 2017;31:114. doi:10.14196/mjiri.31.114
  • Feng JF, Lu L, Dai CM, et al. Analysis of the diagnostic efficiency of serum oxidative stress parameters in patients with breast cancer at various clinical stages. Clin. Biochem. 2016;49(9):692-698. doi:10.1016/j.clinbiochem.2016.02.005
  • Wang M, Dhingra K, Hittelman WN, Liehr JG, de Andrade M, Li D. Lipid peroxidation-induced putative malondialdehyde-DNA adducts in human breast tissues. Cancer Epidemiol Biomarkers Prev. 1996;5(9):705–710.
  • Erel O. A new automated colorimetric method for measuring total oxidant status. Clin. Biochem. 2005;38(12):1103-11. doi:10.1016/j.clinbiochem.2005.08.008
  • Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin. Biochem. 2004;37(2):112-9. doi:10.1016/j.clinbiochem.2003.10.014
  • Kamala HM , EL Sayeda WM, Ibrahemb AH, EL Sokaryc MA, Behiry EG. Study of metallothionein-2A mRNA relative expression and oxidant status in females with breast cancer. Meta Gene. 2020;24:100678. doi:10.1016/j.mgene.2020.100678
  • Rezk NA, Zidan HE, Riad M, Mansy W, Mohamad SA. Metallothionein 2A expression and its relation to different clinical stages and grades of breast cancer in Egyptian patients. Gene. 2015;571(1):17-22. doi:10.1016/j.gene.2015.06.035
  • Panis C, Herrera AC, Victorino VJ, et al. Oxidative stress and hematological profiles of advanced breast cancer patients subjected to paclitaxel or doxorubicin chemotherapy. Breast Cancer Res. Treat. 2012;133(1):89-97. doi:10.1007/s10549-011-1693-x
  • Ramírez-Expósito MJ, Sánchez-López E, Cueto-Ureña C. et al. Circulating oxidative stress parameters in pre- and post-menopausal healthy women and in women suffering from breast cancer treated or not with neoadjuvant chemotherapy. Exp Gerontol. 2014;58:34-42. doi:10.1016/j.exger.2014.07.006
  • Didžiapetrienė J, Kazbarienė B, Tikuišis R, et al. Oxidant/Antioxidant status of breast cancer patients in pre- and post-operative periods. Medicina (Kaunas). 2020;56(2):70. doi:10.3390/medicina56020070
  • Zhou Y, Li H, Xia N. The Interplay between adipose tissue and vasculature: Role of oxidative stress in obesity. Front Cardiovasc Med. 2021;8:650214. doi:10.3389/fcvm.2021.650214
  • Khalil Arjmandi M, Moslemi D, Sadati Zarrini A, et al. Pre and post radiotherapy serum oxidant/antioxidant status in breast cancer patients: Impact of age, BMI and clinical stage of the disease. Rep Pract Oncol Radiother. 2016;21(3):141-148. doi:10.1016/j.rpor.2015.12.009
  • Sateesh R, Rao BAR, Budugu SR, et al. Oxidative stress in relation to obesity in breast cancer. Indian J Cancer. 2019;56(1):41-44. doi:10.4103/ijc.IJC_247_18
  • Pedroza DA, Subramani R, Tiula K, et al. Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation. Lab Invest. 2021;101(6):733-744. doi:10.1038/s41374-021-00594-6
  • Li Y, Yang D, Yin X, et al. Clinicopathological characteristics and breast cancer–specific survival of patients with single hormone receptor–positive breast cancer. JAMA Netw Open. 2020;3(1):e1918160. doi:10.1001/jamanetworkopen.2019.18160
Online Türk Sağlık Bilimleri Dergisi-Cover
  • ISSN: 2459-1467
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2016
  • Yayıncı: Oğuz KARABAY
Sayıdaki Diğer Makaleler

Çocuklarda COVID-19’a İkincil Gelişen Multisistemik İnflamatuar Sendrom Tanılı Hastaların COVID-19 Aşısına Karşı Tutumları

Eviç Zeynep AKGÜN, Dicle AYDIN, Hafize Emine SÖNMEZ, Kadir BABAOĞLU

Covid-19 Pandemisinde Çevrimiçi Kompulsif Satın Alma Davranışı: Kesitsel Bir Çalışma

Havva GEZGİN YAZICI, Müşerref DİDİN

Üç Boyutlu Yazıcı ile Kuğu Boynu Deformitesi için Kişiye Özgü Parmak Ortez Üretimi ve Kullanıcı Memnuniyeti

Eren TİMURTAŞ, Gazi AKGÜN, Ender Ersin AVCI, Neslihan KARABACAK, Gökçe KARTAL, Mine Gülden POLAT, İlkşan DEMİRBÜKEN

Covid-19 Sürecinde Pediatri Hemşirelerinin İzolasyon Önlemlerine Uyum Düzeyleri

Mazlum AYAN, Arzu SARIALİOĞLU

COVID-19 Pandemi Sürecinde Yoğun Bakım Hemşirelerinde Aleksitimi, Empati ve Tükenmişlik Düzeyi Arasındaki İlişkinin İncelenmesi

Aysel ÖZSABAN

Bir Özel Hastanenin Yoğun Bakım Ünitesinde Yatan Hastaların Derin Trakeal Aspirat Örneklerinden İzole Edilen Mikroorganizmalar ve Antibiyotik Duyarlılıkları

Serpil OĞUZ MIZRAKÇI

Sağlık Çalışanlarında Hepatit A, Hepatit B, Hepatit C ve HIV Seroprevalansı

Süleyman KOÇ, Mehmet Reşat CEYLAN, Mehmet ÇELİK, Esra GÜRBÜZ, Fatih ESMER

Bir Üniversite Hastanesi Enfeksiyon Hastalıkları Polikliniğinde Takip Edilen HIV Pozitif Hastaların Aşılanma Durumu

Yasemin ÇAKIR, Nevin İNCE, Emel ÇALIŞKAN

Adolesan Çağındaki Çocuklarda Otoimmün Tiroiditte Parvovirus B19’un Rolü

Cansu DURAK, Zehra YAVAŞ ABALI, Muammer Osman KÖKSAL, Hayati BEKA, Ali AĞAÇFİDAN, Fatma OĞUZ, Firdevs BAŞ

8-14 Yaş Grubu Çocukların COVID-19 Pandemi Döneminde Sağlıkla İlgili Yaşam Kalitelerinin ve Etkileyen Faktörlerin Belirlenmesi

Ülfiye ÇELİKKALP, Aylin YALÇIN IRMAK, Aslıhan OZTURK EYİMAYA